Dynamics and mechanisms of DNA repair by photolyase

Z Liu, L Wang, D Zhong - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
Photolyases, a class of flavoproteins, use blue light to repair two types of ultraviolet-induced
DNA damage, a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) …

The clusters-in-a-liquid approach for solvation: new insights from the conformer specific gas phase spectroscopy and vibrational optical activity spectroscopy

AS Perera, J Thomas, MR Poopari, Y Xu - Frontiers in Chemistry, 2016 - frontiersin.org
Vibrational optical activity spectroscopies, namely vibrational circular dichroism (VCD) and
Raman optical activity (ROA), have been emerged in the past decade as powerful …

Map** hydration dynamics around a protein surface

L Zhang, L Wang, YT Kao, W Qiu… - Proceedings of the …, 2007 - National Acad Sciences
Protein surface hydration is fundamental to its structure and activity. We report here the
direct map** of global hydration dynamics around a protein in its native and molten …

Biological water: A critique

D Zhong, SK Pal, AH Zewail - Chemical Physics Letters, 2011 - Elsevier
In this overview, we provide a critique of the hydration dynamics of macromolecules,
particularly those of protein and DNA. Only in the past decade has femtosecond …

Direct observation of thymine dimer repair in DNA by photolyase

YT Kao, C Saxena, L Wang… - Proceedings of the …, 2005 - National Acad Sciences
Photolyase uses light energy to split UV-induced cyclobutane dimers in damaged DNA, but
its molecular mechanism has never been directly revealed. Here, we report the direct …

Hydration dynamics and time scales of coupled water− protein fluctuations

T Li, AA Hassanali, YT Kao, D Zhong… - Journal of the American …, 2007 - ACS Publications
We report experimental and theoretical studies on water and protein dynamics following
photoexcitation of apomyoglobin. Using site-directed mutation and with femtosecond …

Protein hydration dynamics and molecular mechanism of coupled water− protein fluctuations

L Zhang, Y Yang, YT Kao, L Wang… - Journal of the American …, 2009 - ACS Publications
Protein surface hydration is fundamental to its structural stability and flexibility, and water−
protein fluctuations are essential to biological function. Here, we report a systematic global …

Using low-E resonators to reduce RF heating in biological samples for static solid-state NMR up to 900 MHz

PL Gor'kov, EY Chekmenev, C Li, M Cotten… - Journal of magnetic …, 2007 - Elsevier
RF heating of solid-state biological samples is known to be a destabilizing factor in high-field
NMR experiments that shortens the sample lifetime by continuous dehydration during the …

Ultraviolet superradiance from mega-networks of tryptophan in biological architectures

NS Babcock, G Montes-Cabrera… - The Journal of …, 2024 - ACS Publications
Networks of tryptophan (Trp)─ an aromatic amino acid with strong fluorescence response─
are ubiquitous in biological systems, forming diverse architectures in transmembrane …

Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase

YT Kao, C Tan, SH Song, N Öztürk, J Li… - Journal of the …, 2008 - ACS Publications
We report here our systematic studies of the dynamics of four redox states of the flavin
cofactor in both photolyases and insect type 1 cryptochromes. With femtosecond resolution …