C. elegans in high-throughput drug discovery
LP O'Reilly, CJ Luke, DH Perlmutter… - Advanced drug delivery …, 2014 - Elsevier
Caenorhabditis elegans has been proven to be a useful model organism for investigating
molecular and cellular aspects of numerous human diseases. More recently, investigators …
molecular and cellular aspects of numerous human diseases. More recently, investigators …
[HTML][HTML] Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics
Control of helminth parasites is a key challenge for human and veterinary medicine. In the
absence of effective vaccines and adequate sanitation, prophylaxis and treatment commonly …
absence of effective vaccines and adequate sanitation, prophylaxis and treatment commonly …
EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms
W Stauffer, H Sheng, HN Lim - Scientific reports, 2018 - nature.com
Insight into the function and regulation of biological molecules can often be obtained by
determining which cell structures and other molecules they localize with (ie. colocalization) …
determining which cell structures and other molecules they localize with (ie. colocalization) …
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH)
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
Classifying and segmenting microscopy images with deep multiple instance learning
Motivation: High-content screening (HCS) technologies have enabled large scale imaging
experiments for studying cell biology and for drug screening. These systems produce …
experiments for studying cell biology and for drug screening. These systems produce …
VATA: a poly (vinyl alcohol)-and tannic acid-based nontoxic underwater adhesive
Few studies aiming to develop a glue with an underwater reusable adhesive property have
been reported because combining the two properties of reusable adhesion and underwater …
been reported because combining the two properties of reusable adhesion and underwater …
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
G Günes Günsel, TM Conlon, A Jeridi, R Kim… - Nature …, 2022 - nature.com
Extravasation of monocytes into tissue and to the site of injury is a fundamental
immunological process, which requires rapid responses via post translational modifications …
immunological process, which requires rapid responses via post translational modifications …
Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression
R Kaletsky, V Yao, A Williams, AM Runnels… - PLoS …, 2018 - journals.plos.org
The biology and behavior of adults differ substantially from those of develo** animals, and
cell-specific information is critical for deciphering the biology of multicellular animals. Thus …
cell-specific information is critical for deciphering the biology of multicellular animals. Thus …
[HTML][HTML] Using Machine Learning to make nanomaterials sustainable
Sustainable development is a key challenge for contemporary human societies; failure to
achieve sustainability could threaten human survival. In this review article, we illustrate how …
achieve sustainability could threaten human survival. In this review article, we illustrate how …
Maternal age generates phenotypic variation in Caenorhabditis elegans
Genetically identical individuals that grow in the same environment often show substantial
phenotypic variation within populations of organisms as diverse as bacteria, nematodes …
phenotypic variation within populations of organisms as diverse as bacteria, nematodes …