Recent advances and challenges in temperature monitoring and control in microfluidic devices

AA Dos‐Reis‐Delgado… - …, 2023 - Wiley Online Library
Temperature is a critical—yet sometimes overlooked—parameter in microfluidics.
Microfluidic devices can experience heating inside their channels during operation due to …

Dielectrophoresis of proteins: experimental data and evolving theory

MA Hayes - Analytical and bioanalytical chemistry, 2020 - Springer
The ability to selectively move and trap proteins is core to their effective use as building
blocks and for their characterization. Analytical and preparative strategies for proteins have …

Electrokinetically driven exosome separation and concentration using dielectrophoretic-enhanced PDMS-based microfluidics

S Ayala-Mar, VH Perez-Gonzalez… - Analytical …, 2019 - ACS Publications
Exosomes are a specific subpopulation of extracellular vesicles that have gained interest
because of their many potential biomedical applications. However, exosome isolation and …

Direct current electrokinetic particle trap** in insulator-based microfluidics: theory and experiments

B Cardenas-Benitez, B **d… - Analytical …, 2020 - ACS Publications
The classic theory of direct-current (DC) insulator-based dielectrophoresis (iDEP) considers
that, in order to elicit particle trap**, dielectrophoretic (DEP) velocity counterbalances …

[HTML][HTML] Protein dielectrophoresis: I. Status of experiments and an empirical theory

R Hölzel, R Pethig - Micromachines, 2020 - mdpi.com
The dielectrophoresis (DEP) data reported in the literature since 1994 for 22 different
globular proteins is examined in detail. Apart from three cases, all of the reported protein …

Dielectrophoresis applications in biomedical field and future perspectives in biomedical technology

NN Mohd Maidin, MR Buyong, R A. Rahim… - …, 2021 - Wiley Online Library
Dielectrophoresis (DEP) is a technique to manipulate trajectories of polarisable particles in
nonuniform electric fields by utilizing unique dielectric properties. The manipulation of a cell …

Protein Dielectrophoresis: A Tale of Two Clausius-Mossottis—Or Something Else?

R Pethig - Micromachines, 2022 - mdpi.com
Standard DEP theory, based on the Clausius–Mossotti (CM) factor derived from solving the
boundary-value problem of macroscopic electrostatics, fails to describe the …

Orders-of-magnitude larger force demonstrated for dielectrophoresis of proteins enabling high-resolution separations based on new mechanisms

Y Liu, MA Hayes - Analytical Chemistry, 2020 - ACS Publications
Proteins are perhaps the most important yet frustratingly complicated and difficult class of
compounds to analyze, manipulate, and use. One very attractive option to characterize and …

Protein PEGylation for the design of biobetters: from reaction to purification processes

JHPM Santos, KM Torres-Obreque… - Brazilian Journal of …, 2018 - SciELO Brasil
The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an
important route to develop biobetters for biomedical, biotech and pharmaceutical industries …

Microscale electrokinetic assessments of proteins employing insulating structures

BH Lapizco-Encinas - Current Opinion in Chemical Engineering, 2020 - Elsevier
Microscale electrokinetic systems have offer attractive characteristics for the analysis of
proteins; in particular, systems that rely on both, linear and nonlinear electrokinetic effects …