Recent advances in nanomaterials for the treatment of acute kidney injury

X Ba, T Ye, H Shang, Y Tong, Q Huang… - … Applied Materials & …, 2024 - ACS Publications
Acute kidney injury (AKI) is a serious clinical syndrome with high morbidity, elevated
mortality, and poor prognosis, commonly considered a “sword of Damocles” for hospitalized …

[HTML][HTML] Nanodrugs alleviate acute kidney injury: Manipulate RONS at kidney

Q Chen, Y Nan, Y Yang, Z **ao, M Liu, J Huang… - Bioactive materials, 2023 - Elsevier
Currently, there are no clinical drugs available to treat acute kidney injury (AKI). Given the
high prevalence and high mortality rate of AKI, the development of drugs to effectively treat …

Delivery of nitric oxide with a pH-responsive nanocarrier for the treatment of renal fibrosis

TY Lee, HH Lu, HT Cheng, HC Huang, YJ Tsai… - Journal of Controlled …, 2023 - Elsevier
Fibrosis is an excessive accumulation of extracellular matrix (ECM) that may cause severe
organ dysfunction. Nitric oxide (NO), a multifunctional gaseous signaling molecule, may …

A renal-targeted gene delivery system derived from spermidine for arginase-2 silencing and synergistic attenuation of drug-induced acute kidney injury

XR Gu, K Liu, YX Deng, BX **ang, LY Zhou… - Chemical Engineering …, 2024 - Elsevier
Drug-induced acute kidney injury (DI-AKI) presents a substantial clinical challenge with
limited therapeutic options. This study investigate the potential of arginase-2 (Arg-2) as a …

Dual-responsive curcumin-loaded nanoparticles for the treatment of cisplatin-induced acute kidney injury

T Lan, H Guo, X Lu, K Geng, L Wu, Y Luo… - …, 2022 - ACS Publications
Acute kidney injury (AKI) has been a global public health concern leading to high patient
morbidity and mortality in the world. Nanotechnology-mediated antioxidative therapy has …

[HTML][HTML] Pulmonary fibroblast-specific delivery of siRNA exploiting exosomes-based nanoscaffolds for IPF treatment

H Lu, X Liu, M Zhang, H Bera, W Xu, H Jiang… - Asian Journal of …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that leads to
interstitial inflammation, lung damage, and eventually life-threatening complications. Among …

Self-assembled hyaluronic acid-coated nanocomplexes for targeted delivery of curcumin alleviate acute kidney injury

J Huang, J Guo, Y Dong, H **ao, P Yang, Y Liu… - International Journal of …, 2023 - Elsevier
Acute kidney injury (AKI) is a pathological process with high morbidity, and drug resistance
is easy to occur due to untargeted drug therapy. Curcumin can repair acute kidney injury …

Nanotherapeutics for Alleviating Anesthesia‐Associated Complications

B Lu, L Wei, G Shi, J Du - Advanced Science, 2024 - Wiley Online Library
Current management of anesthesia‐associated complications falls short in terms of both
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …

Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury

Y Wang, H Jiang, L Zhang, P Yao, S Wang… - … in Bioengineering and …, 2023 - frontiersin.org
Acute kidney injury (AKI) is a clinical syndrome that results from a rapid decline in renal
structure or renal functional impairment with the main pathological feature of sublethal and …

Advances in lipid‐based codelivery systems for cancer and inflammatory diseases

CM Jogdeo, S Panja, S Kanvinde… - Advanced …, 2023 - Wiley Online Library
Combination therapy targeting multiple therapeutic targets is a favorable strategy to achieve
better therapeutic outcomes in cancer and inflammatory diseases. Codelivery is a subfield of …