[HTML][HTML] Androgenetic alopecia: An update

S Ntshingila, O Oputu, AT Arowolo, NP Khumalo - JAAD international, 2023 - Elsevier
Androgenetic alopecia (AGA) is the most common nonscarring alopecia and is
characterised by distinct gradual patterned hair loss. AGA is mediated by genetic …

Androgen metabolism and response in prostate cancer anti-androgen therapy resistance

H Zhang, Y Zhou, Z **ng, RK Sah, J Hu… - International journal of …, 2022 - mdpi.com
All aspects of prostate cancer evolution are closely related to androgen levels and the status
of the androgen receptor (AR). Almost all treatments target androgen metabolism pathways …

The enhancement and mechanism of the perception of saltiness by umami peptide from Ruditapes philippinarum and ham

X **e, Y Dang, D Pan, Y Sun, C Zhou, J He, X Gao - Food Chemistry, 2023 - Elsevier
To explore the saltiness enhancement effect and mechanism of umami peptides, umami
peptides from Ruditapes philippinarum and ham were mixed with NaCl and determined …

Identification of novel saltiness-enhancing peptides from yeast extract and their mechanism of action for transmembrane channel-like 4 (TMC4) protein through …

DY Shen, F Pan, ZC Yang, HL Song, T Zou, J **ong… - Food Chemistry, 2022 - Elsevier
Excessive consumption of sodium salt is one of the important inducers of cardiovascular and
cerebrovascular diseases. The reduction of physical labor and attention to health make …

PROTAC degraders of androgen receptor‐integrated dissolving microneedles for androgenetic alopecia and recrudescence treatment via single topical administration

R Wang, T Zhong, Q Bian, S Zhang, X Ma, L Li… - Small …, 2023 - Wiley Online Library
Androgenetic alopecia (AGA) is a transracial and cross‐gender disease worldwide with a
youth‐oriented tendency, but it lacks effective treatment. The binding of androgen receptor …

[HTML][HTML] Saltiness enhancing peptides isolated from enzymolysis extract of Lentinula edodes and their taste enhancing action mechanisms

D Chen, W Chen, D Wu, Z Zhang, P Liu, W Li, Y Yang - LWT, 2023 - Elsevier
The purpose of this study was to identify saltiness-enhancing peptides from continuous
enzymolysis extract of Lentinula edodes by gel filtration chromatography (GFC), LC-MS/MS …

First trans-eunicellane terpene synthase in bacteria

Z Li, B Xu, V Kojasoy, T Ortega, DA Adpressa, W Ning… - Chem, 2023 - cell.com
Terpenoids are the largest family of natural products, but prokaryotes are vastly
underrepresented in this chemical space. However, genomics supports vast untapped …

Decoding of salty/saltiness-enhancing peptides derived from goose hemoglobin and the interaction mechanism with TMC4 receptor

R Wang, X Feng, Z Gong, X Chen, K Cai… - Journal of Agricultural …, 2024 - ACS Publications
Amid the growing concern for health-oriented food choices, salt reduction has received
widespread attention, particularly in the exploitation of salt alternatives. Peptides with a …

Androgens in prostate cancer: A tale that never ends

Z Hou, S Huang, Z Li - Cancer Letters, 2021 - Elsevier
Androgens play an essential role in prostate cancer. Clinical treatments that target
steroidogenesis and the androgen receptor (AR) successfully postpone disease …

[HTML][HTML] A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis

MP Wilson, T Kentache, CR Althoff, C Schulz… - Cell, 2024 - cell.com
Dolichol is a lipid critical for N-glycosylation as a carrier for activated sugars and nascent
oligosaccharides. It is commonly thought to be directly produced from polyprenol by the …