MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …

Background Breast cancer is defined as a biological and molecular heterogeneous disorder
that originates from breast cells. Genetic predisposition is the most important factor giving …

MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …

The decline of oxygen tension in the tissues below the physiological demand leads to the
hypoxic adaptive response. This physiological consequence enables cells to recover from …

Epithelial–mesenchymal transition (EMT) has been implicated in various aspects of tumor
development, including tumor invasion and metastasis, cancer stemness, and therapy …

Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Lactate acidosis is often observed in the tumor microenvironment (TME) of solid tumors. This
is because glucose breaks down quickly via glycolysis, causing lactate acidity. Lactate is …

Tumor cells utilize different strategies to communicate with neighboring tissues for facilitating
tumor progression and invasion, one of these strategies has been shown to be the release …

Breast cancer is one of the most lethal malignancies in women in the world. Various factors
are involved in the development and promotion of the malignancy; most of them involve …

Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …