Functions, Compositions, and Evolution of the Two Types of Carboxysomes: Polyhedral Microcompartments That Facilitate CO2 Fixation in Cyanobacteria and Some …

BD Rae, BM Long, MR Badger… - … and molecular biology …, 2013 - Am Soc Microbiol
Cyanobacteria are the globally dominant photoautotrophic lineage. Their success is
dependent on a set of adaptations collectively termed the CO2-concentrating mechanism …

Reconstruction of biochemical networks in microorganisms

AM Feist, MJ Herrgård, I Thiele, JL Reed… - Nature Reviews …, 2009 - nature.com
Abstract Systems analysis of metabolic and growth functions in microbial organisms is
rapidly develo** and maturing. Such studies are enabled by reconstruction, at the …

FastTree: computing large minimum evolution trees with profiles instead of a distance matrix

MN Price, PS Dehal, AP Arkin - Molecular biology and evolution, 2009 - academic.oup.com
Gene families are growing rapidly, but standard methods for inferring phylogenies do not
scale to alignments with over 10,000 sequences. We present FastTree, a method for …

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

HR Ramage, LE Connolly, JS Cox - PLoS genetics, 2009 - journals.plos.org
Toxin-antitoxin (TA) systems, stress-responsive genetic elements ubiquitous in microbial
genomes, are unusually abundant in the major human pathogen Mycobacterium …

Rapid evolutionary innovation during an Archaean genetic expansion

LA David, EJ Alm - Nature, 2011 - nature.com
The natural history of Precambrian life is still unknown because of the rarity of microbial
fossils and biomarkers,. However, the composition of modern-day genomes may bear …

A bioinformatician's guide to metagenomics

V Kunin, A Copeland, A Lapidus… - Microbiology and …, 2008 - Am Soc Microbiol
As random shotgun metagenomic projects proliferate and become the dominant source of
publicly available sequence data, procedures for the best practices in their execution and …

Environmental genomics reveals a single-species ecosystem deep within Earth

D Chivian, EL Brodie, EJ Alm, DE Culley, PS Dehal… - Science, 2008 - science.org
DNA from low-biodiversity fracture water collected at 2.8-kilometer depth in a South African
gold mine was sequenced and assembled into a single, complete genome. This bacterium …

The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) σ factor protein family

A Staroń, HJ Sofia, S Dietrich, LE Ulrich… - Molecular …, 2009 - Wiley Online Library
The ability of a bacterial cell to monitor and adaptively respond to its environment is crucial
for survival. After one‐and two‐component systems, extracytoplasmic function (ECF) σ …

MicrobesOnline: an integrated portal for comparative and functional genomics

PS Dehal, MP Joachimiak, MN Price… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT Since 2003, MicrobesOnline (http://www. microbesonline. org) has been
providing a community resource for comparative and functional genome analysis. The portal …

Patterns and Implications of Gene Gain and Loss in the Evolution of Prochlorococcus

GC Kettler, AC Martiny, K Huang, J Zucker… - PLoS …, 2007 - journals.plos.org
Prochlorococcus is a marine cyanobacterium that numerically dominates the mid-latitude
oceans and is the smallest known oxygenic phototroph. Numerous isolates from diverse …