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Integrin signaling and cell growth control
Integrins contribute to cell growth by providing a physical linkage between cytoskeletal
structures and the extracellular matrix, and also by participating in various signal …
structures and the extracellular matrix, and also by participating in various signal …
[HTML][HTML] Mechanisms underlying hypoxia-induced neuronal apoptosis
KJ Banasiak, Y ** of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy
The physical properties of particles used in radiation therapy, such as protons, have been
well characterized and their dose distributions are superior to photon-based treatments …
well characterized and their dose distributions are superior to photon-based treatments …
Regulation of the cell cycle by focal adhesion kinase
JH Zhao, H Reiske, JL Guan - The Journal of cell biology, 1998 - rupress.org
In this report, we have analyzed the potential role and mechanisms of integrin signaling
through FAK in cell cycle regulation by using tetracycline-regulated expression of …
through FAK in cell cycle regulation by using tetracycline-regulated expression of …
[PDF][PDF] Targets of oncogenes and tumor suppressors: key for understanding basic mechanisms of carcinogenesis
BP Kopnin - BIOCHEMISTRY C/C OF BIOKHIMIIA, 2000 - protein.bio.msu.ru
Abstract Changes in expression of protooncogenes and tumor suppressor genes play a key
role in oncogenesis. Dysfunction of their protein products leads to abnormal regulation of …
role in oncogenesis. Dysfunction of their protein products leads to abnormal regulation of …
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
J Zhao, R Pestell, JL Guan - Molecular biology of the cell, 2001 - molbiolcell.org
Integrin-mediated cell adhesion to the extracellular matrix is required for normal cell growth.
Cyclin D1 is a key regulator of G1-to-S phase progression of the cell cycle. Our previous …
Cyclin D1 is a key regulator of G1-to-S phase progression of the cell cycle. Our previous …
Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept'of Alzheimer's disease or the yin and yang …
T Arendt - Progress in neurobiology, 2003 - Elsevier
Mental actions are based on the dynamic organization of neuronal networks. In particular,
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
phylogenetically young brain areas (eg, cortical associative circuits) involved in the …
p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice
S Mizuno, HJ Bogaard… - … of Physiology-Lung …, 2011 - journals.physiology.org
Chronic hypoxia induces pulmonary arterial remodeling, resulting in pulmonary
hypertension and right ventricular hypertrophy. Hypoxia has been implicated as a …
hypertension and right ventricular hypertrophy. Hypoxia has been implicated as a …
Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells
Airway remodeling complicates longstanding asthma. It is characterized by an increase in
the number of airway smooth muscle cells (SMCs) as well as an increase in and alteration of …
the number of airway smooth muscle cells (SMCs) as well as an increase in and alteration of …