Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV

S Aherfi, B Pradines, C Devaux, S Honore… - Future …, 2021 - Taylor & Francis
Since the beginning of the COVID-19 pandemic, large in silico screening studies and
numerous in vitro studies have assessed the antiviral activity of various drugs on SARS-CoV …

RETRACTED: Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 Treatment?

PK Agrawal, C Agrawal, G Blunden - Molecules, 2022 - mdpi.com
As the world desperately searches for ways to treat the coronavirus disease 2019 (COVID-
19) pandemic, a growing number of people are turning to herbal remedies. The Artemisia …

Linear versus cubic regression models for analyzing generalized reverse degree based topological indices of certain latest corona treatment drug molecules

M Arockiaraj, AB Greeni… - International Journal of …, 2023 - Wiley Online Library
The major challenges encountered by medical researchers in develo** new drugs are
time consumption, increased cost, establishing a safety profile for the drugs, poor solubility …

In vitro antiviral activity of doxycycline against SARS-CoV-2

M Gendrot, J Andreani, P Jardot, S Hutter, O Delandre… - Molecules, 2020 - mdpi.com
In December 2019, a new severe acute respiratory syndrome coronavirus (SARS-CoV-2),
causing coronavirus disease 2019 (COVID-19), emerged in Wuhan, China. Despite …

[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

M Rudrapal, I Celik, S Chinnam, MA Ansari… - Saudi Journal of …, 2022 - Elsevier
The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …

In Silico molecular docking and dynamic analysis of natural compounds against major non-structural proteins of SARS-COV-2

MU Rehman, A Ali, R Ansar, A Arafah… - Journal of …, 2023 - Taylor & Francis
COVID-19 has infected millions and significantly affected the global economy and
healthcare systems. Despite continuous lockdowns, symptomatic management with …

The striking mimics between COVID-19 and malaria: A review

EHE Konozy, MEM Osman… - Frontiers in …, 2022 - frontiersin.org
Objectives COVID-19 is a transmissible illness triggered by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since its onset in late 2019 in Wuhan city of China …

Molecular docking as a potential approach in repurposing drugs against COVID-19: A systematic review and novel pharmacophore models

M Fadlalla, M Ahmed, M Ali, AA Elshiekh… - Current Pharmacology …, 2022 - Springer
Abstract Purpose of Review This article provides a review of the recent literature related to
the FDA-approved drugs that had been repurposed as potential drug candidates against …

Comprehensive consensus analysis of SARS-CoV-2 drug repurposing campaigns

H Mslati, F Gentile, C Perez… - Journal of Chemical …, 2021 - ACS Publications
The current COVID-19 pandemic has elicited extensive repurposing efforts (both small and
large scale) to rapidly identify COVID-19 treatments among approved drugs. Herein, we …

Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies

S Mousavi, S Zare, M Mirzaei… - Canadian Journal of …, 2022 - Wiley Online Library
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease
outbreak, there has been an increasing interest in discovering potential therapeutic agents …