Advances in genomics technology over recent years have led to the surprising discovery
that the genome is far more pervasively transcribed than was previously appreciated. Much …

Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide
variety of important biological processes. To make easier interpretation of lncRNA …

Antisense transcription, which was initially considered by many as transcriptional noise, is
increasingly being recognized as an important regulator of gene expression. It is …

RNA is not only a messenger operating between DNA and protein. Transcription of
essentially the entire eukaryotic genome generates a myriad of non-protein-coding RNA …

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of …

The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the
scientific and medical communities to interpret the human genome sequence and apply it to …

This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

In the past century, nearly all of the biological sciences have been directly affected by
discoveries and developments in genetics, a fast-evolving subject with important theoretical …

High-throughput sequencing technologies, also known as next-generation sequencing
(NGS) technologies, have revolutionized the way that genomic research is advancing. In …

The incorporation of histone H3 variants has been implicated in the epigenetic memory of
cellular state. Using genome editing with zinc-finger nucleases to tag endogenous H3. 3, we …