Antimicrobial activities and mechanisms of extract and components of herbs in East Asia

J Liang, X Huang, G Ma - RSC advances, 2022 - pubs.rsc.org
Antibacterial drugs face increasing challenges due to drug resistance and adverse
reactions, which has created a pressing need for the discovery and development of novel …

[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

AJ Seukep, V Kuete, L Nahar, SD Sarker… - Journal of pharmaceutical …, 2020 - Elsevier
The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

Anti-Candida albicans natural products, sources of new antifungal drugs: A review

A Zida, S Bamba, A Yacouba… - Journal de mycologie …, 2017 - Elsevier
Introduction Candida albicans is the most prevalent fungal pathogen in humans. Due to the
development of drug resistance, there is today a need for new antifungal agents for the …

The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids

P Amoa Onguéné, F Ntie-Kang, LL Lifongo, JC Ndom… - Malaria journal, 2013 - Springer
Traditional medicine caters for about 80% of the health care needs of many rural
populations around the world, especially in develo** countries. In addition, plant-derived …

AfroDb: a select highly potent and diverse natural product library from African medicinal plants

F Ntie-Kang, D Zofou, SB Babiaka, R Meudom… - PloS one, 2013 - journals.plos.org
Computer-aided drug design (CADD) often involves virtual screening (VS) of large
compound datasets and the availability of such is vital for drug discovery protocols. We …

Potential of Central, Eastern and Western Africa medicinal plants for cancer therapy: spotlight on resistant cells and molecular targets

AT Mbaveng, V Kuete, T Efferth - Frontiers in Pharmacology, 2017 - frontiersin.org
Cancer remains a major health hurdle worldwide and has moved from the third leading
cause of death in the year 1990 to second place after cardiovascular disease since 2013 …

Assessment of phytochemical content, polyphenolic composition, antioxidant and antibacterial activities of Leguminosae medicinal plants in Peninsular Malaysia

YL Chew, EW Ling Chan, PL Tan, YY Lim… - … and alternative medicine, 2011 - Springer
Background Many medicinal plants from Leguminosae family can be found easily in
Malaysia. These plants have been used as traditional medicines by local ethnic groups …

Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery

RS Cheke, HM Patel, VM Patil, IA Ansari, JP Ambhore… - Antibiotics, 2022 - mdpi.com
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids

F Ntie-Kang, PA Onguéné, LL Lifongo, JC Ndom… - Malaria journal, 2014 - Springer
Malaria is currently a public health concern in many countries in the world due to various
factors which are not yet under check. Drug discovery projects targeting malaria often resort …

Phytochemicals with activity against methicillin-resistant Staphylococcus aureus

M Liang, X Ge, H Xua, K Ma, W Zhang, Y Zan, T Efferth… - Phytomedicine, 2022 - Elsevier
Background The evolution of resistance to antimicrobials is a ubiquitous phenomenon. The
evolution of antibiotic resistance in Staphylococcus aureus suggests that there is no remedy …