Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin

A Salminen, K Kaarniranta, A Kauppinen - Inflammation Research, 2022 - Springer
Background Excessive exposure of the skin to UV radiation (UVR) triggers a remodeling of
the immune system and leads to the photoaging state which is reminiscent of chronological …

[HTML][HTML] The role of cellular senescence in skin aging and age-related skin pathologies

T Chin, XE Lee, PY Ng, Y Lee, O Dreesen - Frontiers in physiology, 2023 - frontiersin.org
Aging is the result of a gradual functional decline at the cellular, and ultimately, organismal
level, resulting in an increased risk of develo** a variety of chronic illnesses, such as …

Photoimmunology: how ultraviolet radiation affects the immune system

JJ Bernard, RL Gallo, J Krutmann - Nature Reviews Immunology, 2019 - nature.com
Ultraviolet (UV) radiation is a ubiquitous component of the environment that has important
effects on a wide range of cell functions. Short-wavelength UVB radiation induces sunburn …

Ultraviolet radiation-induced immunosuppression and its relevance for skin carcinogenesis

PH Hart, M Norval - Photochemical & photobiological sciences, 2018 - pubs.rsc.org
The realisation that UV radiation (UVR) exposure could induce a suppressed immune
environment for the initiation of carcinogenesis in the skin was first described more than 40 …

The consequences of UV‐induced immunosuppression for human health

M Norval, GM Halliday - Photochemistry and photobiology, 2011 - Wiley Online Library
Exposure to UV radiation can cause suppression of specific immune responses. The
pathways leading to the down‐regulation are complex, starting from the absorption of UV …

[HTML][HTML] Low temperature and low UV indexes correlated with peaks of influenza virus activity in Northern Europe during 2010–2018

A Ianevski, E Zusinaite, N Shtaida, H Kallio-Kokko… - Viruses, 2019 - mdpi.com
With the increasing pace of global warming, it is important to understand the role of
meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the …

Non-melanoma skin cancer: carcinogenesis and chemoprevention

AC Chen, GM Halliday, DL Damian - Pathology-Journal of the …, 2013 - journals.lww.com
Non-melanoma skin cancer (NMSC) is by far the most frequently diagnosed cancer in
Australia, and exposure to ultraviolet (UV) radiation is the primary cause. Both UVB and UVA …

[HTML][HTML] The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation

SN Byrne, C Beaugie, C O'Sullivan, S Leighton… - The American journal of …, 2011 - Elsevier
The cellular and molecular mechanisms by which UV radiation modulates inflammation and
immunity while simultaneously maintaining skin homeostasis is complex and not completely …

UVA1 phototherapy: a review of mechanism and therapeutic application

NR York, HT Jacobe - International journal of dermatology, 2010 - Wiley Online Library
Ultraviolet radiation (UVR) phototherapy has been associated with both deleterious and
beneficial effects to patients with both localized and systemic skin disorders. Phototherapy is …

Role of ultraviolet radiation in papillomavirus-induced disease

A Uberoi, S Yoshida, IH Frazer, HC Pitot… - PLoS …, 2016 - journals.plos.org
Human papillomaviruses are causally associated with 5% of human cancers. The recent
discovery of a papillomavirus (MmuPV1) that infects laboratory mice provides unique …