Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis

IP Trougakos, E Terpos, H Alexopoulos… - Trends in Molecular …, 2022 - cell.com
Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19)
pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is …

Overview of autoantibodies in COVID‐19 convalescents

K Dobrowolska, D Zarębska‐Michaluk… - Journal of medical …, 2023 - Wiley Online Library
Accumulating evidence shows that SARS‐CoV‐2 can potentially trigger autoimmune
processes, which can be responsible for the long‐term consequences of COVID‐19 …

Potential autoimmunity resulting from molecular mimicry between SARS-CoV-2 spike and human proteins

J Nunez-Castilla, V Stebliankin, P Baral, CA Balbin… - Viruses, 2022 - mdpi.com
Molecular mimicry between viral antigens and host proteins can produce cross-reacting
antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a …

Contrastive learning on protein embeddings enlightens midnight zone

M Heinzinger, M Littmann, I Sillitoe… - NAR genomics and …, 2022 - academic.oup.com
Experimental structures are leveraged through multiple sequence alignments, or more
generally through homology-based inference (HBI), facilitating the transfer of information …

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …

Drug-repurposing screening identifies a gallic acid binding site on SARS-CoV-2 non-structural protein 7

Y Gu, M Liu, BL Staker, GW Buchko… - ACS Pharmacology & …, 2023 - ACS Publications
SARS-CoV-2 is the agent responsible for acute respiratory disease COVID-19 and the
global pandemic initiated in early 2020. While the record-breaking development of vaccines …

Epigenetic rewiring of pathways related to odour perception in immune cells exposed to SARS-CoV-2 in vivo and in vitro

J Huoman, S Sayyab, E Apostolou, L Karlsson… - Epigenetics, 2022 - Taylor & Francis
ABSTRACT A majority of SARS-CoV-2 recoverees develop only mild-to-moderate
symptoms, while some remain completely asymptomatic. Although viruses, including SARS …

T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures

J Xu, X Li, N Yuan, C Li, J Yang, L Cheng, Z Lu… - Frontiers in …, 2023 - frontiersin.org
Background The immune responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are crucial in maintaining a delicate balance between protective effects and …

Scalable Inhibitors of the Nsp3–Nsp4 Coupling in SARS-CoV-2

AR Azizogli, V Pai, F Coppola, R Jafari, JB Dodd-o… - ACS …, 2023 - ACS Publications
The human Betacoronavirus SARS-CoV-2 is a novel pathogen claiming millions of lives and
causing a global pandemic that has disrupted international healthcare systems, economies …

Evidence for Molecular Mimicry between SARS‐CoV‐2 and Human Antigens: Implications for Autoimmunity in COVID‐19

A Arévalo-Cortés, D Rodriguez-Pinto… - Autoimmune …, 2024 - Wiley Online Library
As for other viral diseases, the mechanisms behind the apparent relationship between
COVID‐19 and autoimmunity are yet to be clearly defined. Molecular mimicry, the existence …