Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Azobenzene is a well‐known derivative of stimulus‐responsive molecular switches and has
shown superior performance as a functional material in biomedical applications. The results …

Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …

A large proportion of protein–protein interactions (PPIs) occur between a short peptide and a
globular protein domain; the peptides involved in surface interactions play important roles …

Protein–protein interactions (PPIs) are involved at all levels of cellular organization, thus
making the development of PPI inhibitors extremely valuable. The identification of selective …

Controlling the conformation and activity of biomolecules in a reversible manner is a
fascinating challenge (1-3) that has an outstanding potential for the study of and interference …

Peptide stapling is a strategy for constraining short peptides typically in an alpha-helical
conformation. Stapling is carried out by covalently linking the side-chains of two amino …

The photoisomerization of azobenzene has been known for almost 75 years but only
recently has this process been widely applied to biological systems. The central challenge of …

Most azobenzene-based photoswitches use UV light for photoisomerization. This can limit
their application in biological systems, where UV light can trigger unwanted responses …

We report the discovery of a facile transformation between perfluoroaromatic molecules and
a cysteine thiolate, which is arylated at room temperature. This new approach enabled us to …