The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …

Conspectus Over the past decades, major efforts were undertaken to develop devices on a
nanoscale level for the efficient and nontoxic delivery of molecules to tissues and cells, for …

The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

Nanoparticles are defined as a group of particles having sizes between 1 and 100 nm and
characterized by some specific physicochemical properties such as surface area, surface …

Nanoparticles (NPs) represent an important advance for delivering diagnostic and
therapeutic agents across the blood–brain barrier. However, NP clearance is critical for …

Nanotechnology is a multidisciplinary science covering matters involving the nanoscale
level that is being developed for a great variety of applications. Nanomedicine is one of …

Nanoparticles (NPs) are currently used in diagnosis and treatment of many human diseases,
including autoimmune diseases and cancer. However, cytotoxic effects of NPs on normal …

Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

Nanotechnology has emerged as one of the leading fields of the science having tremendous
application in diverse disciplines. As nanomaterials are increasingly becoming part of …