[HTML][HTML] Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

S Halldorsson, E Lucumi, R Gómez-Sjöberg… - Biosensors and …, 2015 - Elsevier
Culture of cells using various microfluidic devices is becoming more common within
experimental cell biology. At the same time, a technological radiation of microfluidic cell …

Microfluidics for sperm analysis and selection

R Nosrati, PJ Graham, B Zhang, J Riordon… - Nature Reviews …, 2017 - nature.com
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

Microfluidic platforms for mechanobiology

WJ Polacheck, R Li, SGM Uzel, RD Kamm - Lab on a Chip, 2013 - pubs.rsc.org
Mechanotransduction has been a topic of considerable interest since early studies
demonstrated a link between mechanical force and biological response. Until recently …

3D printing of soft lithography mold for rapid production of polydimethylsiloxane-based microfluidic devices for cell stimulation with concentration gradients

K Kamei, Y Mashimo, Y Koyama, C Fockenberg… - Biomedical …, 2015 - Springer
Abstract Three-dimensional (3D) printing is advantageous over conventional technologies
for the fabrication of sophisticated structures such as 3D micro-channels for future …

Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients

BM Baker, B Trappmann, SC Stapleton, E Toro… - Lab on a Chip, 2013 - pubs.rsc.org
Gradients of diffusive molecules within 3D extracellular matrix (ECM) are essential in
guiding many processes such as development, angiogenesis, and cancer. The spatial …

Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

PM Davidson, J Sliz, P Isermann, C Denais… - Integrative …, 2015 - academic.oup.com
The ability of cells to migrate through tissues and interstitial spaces is an essential factor
during development and tissue homeostasis, immune cell mobility, and in various human …

Mechanical guidance of cell migration: lessons from chemotaxis

P Roca-Cusachs, R Sunyer, X Trepat - Current opinion in cell biology, 2013 - Elsevier
For an organism to develop, for a wound to heal, or for a tumor to invade, cells must be able
to migrate following directional cues. It is widely accepted that directed cell migration is …

Recent developments in microfluidics-based chemotaxis studies

J Wu, X Wu, F Lin - Lab on a Chip, 2013 - pubs.rsc.org
Microfluidic devices can better control cellular microenvironments compared to conventional
cell migration assays. Over the past few years, microfluidics-based chemotaxis studies …

Host‐microbe interaction in the gastrointestinal tract

A Parker, MAE Lawson, L Vaux… - Environmental …, 2018 - Wiley Online Library
The gastrointestinal tract is a highly complex organ in which multiple dynamic physiological
processes are tightly coordinated while interacting with a dense and extremely diverse …

Patterns of bacterial motility in microfluidics-confining environments

V Tokárová, A Sudalaiyadum Perumal… - Proceedings of the …, 2021 - National Acad Sciences
Understanding the motility behavior of bacteria in confining microenvironments, in which
they search for available physical space and move in response to stimuli, is important for …