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Computational models in cardiology
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to …
Critical care, like many healthcare areas, is under a dual assault from significantly
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
Biological research and self-driving labs in deep space supported by artificial intelligence
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …
organisms, develop foundational knowledge to support deep space exploration and …
[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …
wherein biophysically detailed core models describe the different physical processes …
Verification of cardiac tissue electrophysiology simulators using an N-version benchmark
Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …
of advanced and increasingly complex computational frameworks for simulating cardiac …
Modelling the lymphatic system: challenges and opportunities
KN Margaris, RA Black - Journal of the Royal Society …, 2012 - royalsocietypublishing.org
The lymphatic system is a vital part of the circulatory and immune systems, and plays an
important role in homeostasis by controlling extracellular fluid volume and in combating …
important role in homeostasis by controlling extracellular fluid volume and in combating …
Fully coupled fluid‐electro‐mechanical model of the human heart for supercomputers
A Santiago, J Aguado‐Sierra… - … journal for numerical …, 2018 - Wiley Online Library
In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …
Calibration of ionic and cellular cardiac electrophysiology models
Cardiac electrophysiology models are among the most mature and well‐studied
mathematical models of biological systems. This maturity is bringing new challenges as …
mathematical models of biological systems. This maturity is bringing new challenges as …
[HTML][HTML] A machine learning method for real-time numerical simulations of cardiac electromechanics
We propose a machine learning-based method to build a system of differential equations
that approximates the dynamics of 3D electromechanical models for the human heart …
that approximates the dynamics of 3D electromechanical models for the human heart …