HLA frequencies show widespread variation across human populations. Demographic
factors as well as selection are thought to have shaped HLA variation across continents. In …

The ideal vaccines for combating diseases that may emerge in the future require more than
simply inactivating a few pathogenic strains. This study aims to provide a peptide-based …

We studied HLA class I (HLA-A,-B) and class II (HLA-DRB1,-DQB1) allele groups and alleles
by PCR-SSP based ty** in a total of 15,318 mixed ancestry Mexicans from all the states of …

Major histocompatibility complex (MHC) genes are highly polymorphic and informative in
disease association, transplantation, and population genetics studies with particular …

Hematopoietic cell transplantation (HCT) is in many cases the only curative approach to
treat patients with hematologic malignant diseases. In addition, it is used to treat …

Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native
American using a high-resolution next generation sequencing (NGS) method. We assessed …

BACKGROUND Primary biliary cholangitis (PBC) is a serious disease that causes significant
morbidity. PBC is confirmed with liver biopsy but autoantibodies are frequently used as …

Several studies have implicated HLA in non-Hodgkin lymphoma (NHL) subtype etiology.
However, NHL patients indicated for stem cell transplants are underrepresented in these …

This chapter provides a brief revision of the most relevant work on biological markers and
diseases that have contributed to the field of biodemography in Central America and …

Guatemala is a country located in Central America, and while it is one of the most populated
countries in the region, the genetic diversity of the population has been poorly analyzed …