At the most fundamental level, the bowel facilitates absorption of small molecules, regulates
fluid and electrolyte flux, and eliminates waste. To successfully coordinate this complex …

Weight gain during antidepressant treatment can be either a sign of improvement in patients
who have weight loss as a symptom of depression or a residual symptom in patients who …

This revision of the 2005 British Association for Psychopharmacology guidelines for the
evidence-based pharmacological treatment of anxiety disorders provides an update on key …

Background: There are difficulties with the diagnosis of serotonin toxicity, particularly with
the use of Sternbach's criteria. Aim: To improve the criteria for diagnosing clinically …

Background: Selective serotonin reuptake inhibitors (SSRIs) have increasingly replaced
tricyclic antidepressants (TCAs) in the treatment of depression. They appear to be safer in …

ContextA neonatal behavioral syndrome linked to in utero serotonin reuptake inhibitor (SRI)
exposure during the last trimester of pregnancy has been identified. The US Food and Drug …

This paper reviews the preclinical and clinical evidence regarding the use of the dietary
supplement 5-hydroxytryptophan (5-HTP) for the treatment of depression. In the absence of …

Serotonin syndrome is caused by drug induced excess of intrasynaptic 5-hydroxytryptamine.
The clinical manifestations are mediated by the action of 5-hydroxytryptamine on various …

A. Peripherally acting agents B. Centrally acting agents IV. Drugs That Alter Metabolism A.
Preabsorptive agents B. Postabsorptive modifiers of nutrient metabolism V. Drugs That …

Background No drugs are approved for treatment of premature ejaculation. Our aim was to
determine the efficacy and tolerability of on-demand dapoxetine in patients with severe …