Nitric oxide (NO) and nociceptive processing in the spinal cord
ST Meller, GF Gebhart - Pain, 1993 - Elsevier
There is considerable evidence to implicate N-methyl-d-aspartate (NMDA) receptor
activation in the mechanisms that underly thermal hyperalgesia in the spinal cord. As many …
activation in the mechanisms that underly thermal hyperalgesia in the spinal cord. As many …
Regulatory role of nitric oxide in cutaneous inflammation
MQ Man, JS Wakefield, TM Mauro, PM Elias - Inflammation, 2022 - Springer
Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple
organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …
organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.
JR Vane, JA Mitchell, I Appleton… - Proceedings of the …, 1994 - National Acad Sciences
Cyclooxygenase (COX) converts arachidonic acid to prostaglandin H2, which is further
metabolized to prostanoids. Two isoforms of COX exist: a constitutive (COX-1) and an …
metabolized to prostanoids. Two isoforms of COX exist: a constitutive (COX-1) and an …
Modulation of acute inflammation by endogenous nitric oxide
A Ialenti, A Ianaro, S Moncada, M Di Rosa - European journal of …, 1992 - Elsevier
The role of endogenous nitric oxide (NO) in acute inflammation was investigated using two
inhibitors of NO synthase (N G-nitro-L-arginine methyl ester (L-NAME) and N G-monomethyl …
inhibitors of NO synthase (N G-nitro-L-arginine methyl ester (L-NAME) and N G-monomethyl …
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
R Björkman - Acta Anaesthesiologica Scandinavica. Supplementum, 1995 - europepmc.org
Background These studies were undertaken to investigate the site and nature of the
antinociceptive effect of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and paracetamol …
antinociceptive effect of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and paracetamol …
Sensory neuropeptides: their role in inflammation and wound healing
SD Brain - Immunopharmacology, 1997 - Elsevier
Vasoactive neuropeptides including substance P and calcitonin gene-related peptide
(CGRP) are localised in sensory nerves which innervate blood vessels. These are the major …
(CGRP) are localised in sensory nerves which innervate blood vessels. These are the major …
The NO cascade, eNOS location, and microvascular permeability
WN Durán, JW Breslin, FA Sanchez - Cardiovascular research, 2010 - academic.oup.com
The nitric oxide (NO) cascade and endothelial NO synthase (eNOS) are best known for their
role in endothelium-mediated relaxation of vascular smooth muscle. Activation of eNOS by …
role in endothelium-mediated relaxation of vascular smooth muscle. Activation of eNOS by …
The 1991 Ulf von Euler Lecture:The l‐arginine: nitric oxide pathway
S Moncada - Acta physiologica Scandinavica, 1992 - Wiley Online Library
The 1991 Ulf von Euler Lecture:The <sc>l</sc>â•’arginine: nitric oxide pathway Page 1 Acta
Physiol Scad 1992, 145, 201--227 The 1991 Ulf von Euler Lecture The L-arginine : nitric oxide …
Physiol Scad 1992, 145, 201--227 The 1991 Ulf von Euler Lecture The L-arginine : nitric oxide …
TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice
T Miyamoto, AE Dubin, MJ Petrus, A Patapoutian - PloS one, 2009 - journals.plos.org
Nitric oxide (NO) can induce acute pain in humans and plays an important role in pain
sensitization caused by inflammation and injury in animal models. There is evidence that NO …
sensitization caused by inflammation and injury in animal models. There is evidence that NO …
Myocardial reperfusion injury: etiology, mechanisms, and therapies
JW Hoffman, TB Gilbert, RS Poston… - The Journal of …, 2004 - ject.edpsciences.org
Reperfusion of ischemic myocardium is required for tissue survival; however, reperfusion
elicits pathologic consequences. Myocardial reperfusion injury is a multifarious process that …
elicits pathologic consequences. Myocardial reperfusion injury is a multifarious process that …