[HTML][HTML] Bowman-Birk inhibitors: Insights into family of multifunctional proteins and peptides with potential therapeutical applications

A Gitlin-Domagalska, A Maciejewska, D Dębowski - Pharmaceuticals, 2020 - mdpi.com
Bowman-Birk inhibitors (BBIs) are found primarily in seeds of legumes and in cereal grains.
These canonical inhibitors share a highly conserved nine-amino acids binding loop motif …

Chia expeller: A promising source of antioxidant, antihypertensive and antithrombotic peptides produced by enzymatic hydrolysis with Alcalase and Flavourzyme

B Ozón, J Cotabarren, T Valicenti, MG Parisi… - Food Chemistry, 2022 - Elsevier
Chia expeller is a promising source of bioactive compounds suitable for the development of
nutraceutical ingredients due to its functional, biological, and nutritional properties. In this …

[PDF][PDF] Phytochemistry and pharmacological activities of Ficus carica latex: A systematic review

H Mohammad, M Alzweiri - Journal of Chinese Pharmaceutical …, 2022 - researchgate.net
Ficus carica tree produces a white sap that is traditionally used for the treatment of skin
conditions, such as warts. Ficus carica latex is considered a rich source of proteins and …

A multifunctional trypsin protease inhibitor from yellow bell pepper seeds: Uncovering its dual antifungal and hypoglycemic properties

J Cotabarren, B Ozón, S Claver, F Geier, M Rossotti… - Pharmaceutics, 2023 - mdpi.com
Fungal infections are a growing public health concern worldwide and the emergence of
antifungal resistance has limited the number of therapeutic options. Therefore, develo** …

Uniform PtCoRuRhFe high-entropy alloy nanoflowers: Multi-site synergistic signal amplification for colorimetric assay of captopril

R Zhang, JQ Li, AJ Wang, P Song, W Liu, JJ Feng… - Microchimica Acta, 2024 - Springer
Uniform PtCoRuRhFe high-entropy alloy nanoflowers (HEANFs) were fabricated by a simple
wet-chemical co-reduction method in oleylamine for quantitative colorimetric determination …

[HTML][HTML] Engineering and structural insights of a novel BBI-like protease inhibitor Livisin from the frog skin secretion

J Yang, C Tong, J Qi, X Liao, X Li, X Zhang, M Zhou… - Toxins, 2022 - mdpi.com
The Bowman–Birk protease inhibitor (BBI) family is a prototype group found mainly in plants,
particularly grasses and legumes, which have been subjected to decades of study. Recently …

Purification and Characterization of a Novel Thermostable Papain Inhibitor from Moringa oleifera with Antimicrobial and Anticoagulant Properties

J Cotabarren, S Claver, JA Payrol, J Garcia-Pardo… - Pharmaceutics, 2021 - mdpi.com
Plant cystatins (or phytocystatins) comprise a large superfamily of natural bioactive small
proteins that typically act as protein inhibitors of papain-like cysteine proteases. In this …

Inhibitory potential of recombinant and native peanut Bowman-Birk inhibitor against proteases of human blood coagulation pathway

V Lokya, M Swathi, SS Mohanraj, K Padmasree - Food Bioscience, 2024 - Elsevier
Plant proteinase/protease inhibitors (PIs) have therapeutic potential besides their role in
regulating endogenous protease activity in several physiological processes. They exert their …

Chia (Salvia hispanica L.) Seeds Contain a Highly Stable Trypsin Inhibitor with Potential for Bacterial Management Alone or in Drug Combination Therapy with …

AÁ De Souza, AM Lima… - Probiotics and …, 2023 - Springer
The emergence of antibiotic resistance poses a serious and challenging threat to healthcare
systems, making it imperative to discover novel therapeutic options. This work reports the …

Recent Advancements in Novel Bioactive Peptides and Protein Hydrolysates Isolated from Different Medicinal Plants Along with Their Applications in Food and …

V Sharma, P Gupta, P Sharma - International Journal of Peptide Research …, 2023 - Springer
Bioactive peptides and protein hydrolysates are recently gaining importance. Being
functionally active they are used as ingredients in products like fortified fermented dairy …