Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …

The procedure of neurogenesis has made numerous achievements in the past decades,
during which various molecular biomarkers have been emerging and have been broadly …

Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …

Heat shock proteins (Hsps) are a large family of molecular chaperones that are well-known
for their roles in protein maturation, re-folding and degradation. While some Hsps are …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

The ocular lens is a model system for understanding important aspects of embryonic
development, such as cell specification and the spatiotemporally controlled formation of a …

Eye development has been a paradigm for the study of organogenesis, from the
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …

During the past two decades, induced pluripotent stem cells (iPSCs) have been widely used
to study human neural development and disease. Especially in the field of Alzheimer's …

The mammalian cerebral cortex is the pinnacle of brain evolution, reaching its maximum
complexity in terms of neuron number, diversity and functional circuitry. The emergence of …

We are exploring the mechanisms underlying how maternal infection increases the risk for
schizophrenia and autism in the offspring. Several mouse models of maternal immune …