Cationic polymers as transfection reagents for nucleic acid delivery
Nucleic acid therapy can achieve lasting and even curative effects through gene
augmentation, gene suppression, and genome editing. However, it is difficult for naked …
augmentation, gene suppression, and genome editing. However, it is difficult for naked …
A review of non-invasive drug delivery through respiratory routes
YB Zhang, D Xu, L Bai, YM Zhou, H Zhang, YL Cui - Pharmaceutics, 2022 - mdpi.com
With rapid and non-invasive characteristics, the respiratory route of administration has
drawn significant attention compared with the limitations of conventional routes. Respiratory …
drawn significant attention compared with the limitations of conventional routes. Respiratory …
The upper nasal space: Option for systemic drug delivery, mucosal vaccines and “Nose-to-Brain”
SB Shrewsbury - Pharmaceutics, 2023 - mdpi.com
Sino-nasal disease is appropriately treated with topical treatment, where the nasal mucosa
acts as a barrier to systemic absorption. Non-invasive nasal delivery of drugs has produced …
acts as a barrier to systemic absorption. Non-invasive nasal delivery of drugs has produced …
Paclitaxel delivery to the brain for glioblastoma treatment
M AbdEl-Haq, A Kumar, F Ait Mohand… - International Journal of …, 2023 - mdpi.com
The development of paclitaxel-loaded polymeric nanoparticles for the treatment of brain
tumors was investigated. Poly (lactide-glycolide)(PLGA) nanoparticles containing 10% w/w …
tumors was investigated. Poly (lactide-glycolide)(PLGA) nanoparticles containing 10% w/w …
Bovine serum albumin nanoparticles enhanced the intranasal bioavailability of silybin in rats
APS Tartari, SH Peczek, MT Fin, J Ziebarth… - Pharmaceutics, 2023 - mdpi.com
Silybin (SLB), an important flavonoid from silymarin, displays significant hepatoprotective,
anticancer, antioxidant, and neuroprotective effects. However, its therapeutic efficacy is …
anticancer, antioxidant, and neuroprotective effects. However, its therapeutic efficacy is …