Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds

G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …

Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

[HTML][HTML] A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities

SO Sarrigiannidis, JM Rey, O Dobre… - Materials Today Bio, 2021 - Elsevier
Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Bone matrix non-collagenous proteins in tissue engineering: Creating new bone by mimicking the extracellular matrix

MS Carvalho, JMS Cabral, CL da Silva, D Vashishth - Polymers, 2021 - mdpi.com
Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …

[HTML][HTML] Stem cell niche-inspired microcarriers with ADSCs encapsulation for diabetic wound treatment

X Wu, H Zhu, J Che, Y Xu, Q Tan, Y Zhao - Bioactive materials, 2023 - Elsevier
Stem cell therapies have made great progress in the treatment of diabetic wounds during
recent decades, while their short in vivo residence, alloimmune reactions, undesired …

Wound microenvironment-responsive protein hydrogel drug-loaded system with accelerating healing and antibacterial property

R Zhang, Y Tian, L Pang, T Xu, B Yu… - … Applied Materials & …, 2022 - ACS Publications
Growth factors play a vital role in wound healing, and novel hydrogel carriers suitable for
growth factors have always been a research hotspot in the wound healthcare field. In this …

Hydrogel drug delivery systems for bone regeneration

L Bai, G Tao, M Feng, Y **e, S Cai, S Peng, J **ao - Pharmaceutics, 2023 - mdpi.com
With the in-depth understanding of bone regeneration mechanisms and the development of
bone tissue engineering, a variety of scaffold carrier materials with desirable …

Hydrogels for bone organoid construction: From a materiobiological perspective

S Wu, X Wu, X Wang, J Su - Journal of materials science & technology, 2023 - Elsevier
Bone organoids, which simulate and construct special organs in vitro with complex
biological functions based on tissue engineering technology, provide dramatically realistic …

ECM‐Inspired Hydrogels with ADSCs Encapsulation for Rheumatoid Arthritis Treatment

H Zhu, X Wu, R Liu, Y Zhao, L Sun - Advanced Science, 2023 - Wiley Online Library
Due to their intrinsic anti‐inflammatory and immunomodulatory properties, adipose‐derived
stem cells (ADSCs) are explored as a promising alternative in treating rheumatoid arthritis …