As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor
immunotherapy. Taking into account the many recent advances in DC biology, we discuss …

Antibodies are essential components of an adaptive immune response. Immunoglobulin G
(IgG) is the most common type of antibody found in circulation and extracellular fluids …

The effectiveness of a drug is dependent on accumulation at the site of action at therapeutic
levels, however, challenges such as rapid renal clearance, degradation or non-specific …

The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies
of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for …

Introduction: Many of the biotherapeutics approved or under development suffer from a short
half-life necessitating frequent applications in order to maintain a therapeutic concentration …

Highlights•A variety of albumin-binding moieties (ABMs) have been developed for half-life
extension of short-lived drugs.•Various drugs can incorporate a selected ABM for in situ HSA …

Albumin is the most abundant protein in blood and acts as a molecular taxi for a plethora of
small insoluble substances such as nutrients, hormones, metals and toxins. In addition, it …

Magnetic nanoparticles (MNPs) have great potential in biochemistry and medical science. In
particular, iron oxide nanoparticles have demonstrated a promising effect in various …

Introduction A poor pharmacokinetic profile due to inadequate distribution and rapid renal
clearance limits site-specific target engagement and drug efficacy. The inherent properties of …

Oral delivery of biopharmaceuticals, as insulin, is hampered by rapid degradation and
inefficient absorption in the gastrointestinal tract (GIT). To solve this, a new class of …