Lycium barbarum polysaccharides: Extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review

A Masci, S Carradori, MA Casadei, P Paolicelli… - Food chemistry, 2018 - Elsevier
In the last decades, glycoconjugates from Lycium barbarum L. fruit (Goji berry) have
received a great attention for their potential health-promoting effects. The present review …

Circadian etiology of type 2 diabetes mellitus

N Javeed, AV Matveyenko - Physiology, 2018 - journals.physiology.org
The epidemic of Type 2 diabetes mellitus necessitates development of novel therapeutic
and preventative strategies to attenuate expansion of this debilitating disease. Evidence …

[HTML][HTML] Circadian clock network desynchrony promotes weight gain and alters glucose homeostasis in mice

I Kolbe, B Leinweber, M Brandenburger, H Oster - Molecular Metabolism, 2019 - Elsevier
Objective A network of endogenous circadian clocks adapts physiology and behavior to
recurring changes in environmental demands across the 24-hour day cycle. Circadian …

Adropin as a potential mediator of the metabolic system‐autonomic nervous system‐chronobiology axis: Implementing a personalized signature‐based platform for …

Y Kolben, S Weksler‐Zangen, Y Ilan - Obesity Reviews, 2021 - Wiley Online Library
Adropin is a peptide hormone, which plays a role in energy homeostasis and controls
glucose and fatty acid metabolism. Its levels correlate with changes in carbohydrate‐lipid …

Clocks, rhythms, sex, and hearts: How disrupted circadian rhythms, time-of-day, and sex influence cardiovascular health

OH Meléndez-Fernández, JC Walton, AC DeVries… - Biomolecules, 2021 - mdpi.com
Cardiovascular diseases are the top cause of mortality in the United States, and ischemic
heart disease accounts for 16% of all deaths around the world. Modifiable risk factors such …

Chronomedicine and type 2 diabetes: shining some light on melatonin

AC Forrestel, SU Miedlich, M Yurcheshen, SD Wittlin… - Diabetologia, 2017 - Springer
In mammals, the circadian timing system drives rhythms of physiology and behaviour,
including the daily rhythms of feeding and activity. The timing system coordinates temporal …

Administration of melatonin and metformin prevents deleterious effects of circadian disruption and obesity in male rats

AP Thomas, J Hoang, K Vongbunyong… - …, 2016 - academic.oup.com
Circadian disruption and obesity synergize to predispose to development of type 2 diabetes
mellitus (T2DM), signifying that therapeutic targeting of both circadian and metabolic …

Circadian disruption and diet-induced obesity synergize to promote development of β-cell failure and diabetes in male rats

J Qian, B Yeh, K Rakshit, CS Colwell… - …, 2015 - academic.oup.com
There are clear epidemiological associations between circadian disruption, obesity, and
pathogenesis of type 2 diabetes. The mechanisms driving these associations are unclear. In …

[HTML][HTML] Eating on nightshift: a big vs small snack impairs glucose response to breakfast

S Centofanti, J Dorrian, C Hilditch, C Grant… - Neurobiology of sleep …, 2018 - Elsevier
Shift work is a risk factor for chronic diseases such as Type 2 diabetes. Food choice may
play a role, however simply eating at night when the body is primed for sleep may have …

Circadian variation of the pancreatic islet transcriptome

K Rakshit, J Qian, J Ernst… - Physiological …, 2016 - journals.physiology.org
Pancreatic islet failure is a characteristic feature of impaired glucose control in diabetes
mellitus. Circadian control of islet function is essential for maintaining proper glucose …