Many microorganisms live in communities and depend on metabolites secreted by fellow
community members for survival. Yet our knowledge of interspecies metabolic …

Multidrug/Multixenobiotic resistance (MDR/MXR) is a widespread phenomenon with clinical,
agricultural and biotechnological implications, where MDR/MXR transporters that are …

The YEASTRACT+ information system (http://YEASTRACT-PLUS. org/) is a wide-scope tool
for the analysis and prediction of transcription regulatory associations at the gene and …

Abstract YEASTRACT+ (http://yeastract-plus. org/) is a tool for the analysis, prediction and
modelling of transcription regulatory data at the gene and genomic levels in yeasts. It …

Doxorubicin is one of the most effective chemotherapy drugs used against solid tumors in
the treatment of several cancer types. Two different mechanisms,(i) intercalation of …

Synthetic promoters, especially minimally sized, are critical for advancing fungal synthetic
biology. Fungal promoters often span hundreds of base pairs, nearly ten times the amount of …

Overexpression experiments are sometimes considered as qualitative experiments
designed to identify novel proteins and study their function. However, in order to draw …

Abstract The YEAst Search for Transcriptional Regulators And Consensus Tracking
(YEASTRACT—www. yeastract. com) information system has been, for 11 years, a key tool …

The establishment of a heterologous pathway in a microbial host for the production of
industrially relevant chemicals at high titers and yields requires efficient adjustment of the …

A major goal of systems biology is to build predictive computational models of cellular
metabolism. Availability of complete genome sequences and wealth of legacy biochemical …