The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

JW Fahey, AT Zalcmann, P Talalay - Phytochemistry, 2001 - Elsevier
Glucosinolates (β-thioglucoside-N-hydroxysulfates), the precursors of isothiocyanates, are
present in sixteen families of dicotyledonous angiosperms including a large number of …

[HTML][HTML] Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants

I Blažević, S Montaut, F Burčul, CE Olsen, M Burow… - Phytochemistry, 2020 - Elsevier
The glucosinolates (GSLs) is a well-defined group of plant metabolites characterized by
having an S-β-d-glucopyrano unit anomerically connected to an O-sulfated (Z) …

Biology and biochemistry of glucosinolates

BA Halkier, J Gershenzon - Annu. Rev. Plant Biol., 2006 - annualreviews.org
Glucosinolates are sulfur-rich, anionic natural products that upon hydrolysis by endogenous
thioglucosidases called myrosinases produce several different products (eg …

Structural and sequence-based classification of glycoside hydrolases

B Henrissat, G Davies - Current opinion in structural biology, 1997 - Elsevier
The diversity of oligo-and polysaccharides provides an abundance of biological roles for
these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases …

A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense

P Bednarek, M Pislewska-Bednarek, A Svatoš… - Science, 2009 - science.org
Selection pressure exerted by insects and microorganisms shapes the diversity of plant
secondary metabolites. We identified a metabolic pathway for glucosinolates, known insect …

Glycosidase mechanisms: anatomy of a finely tuned catalyst

DL Zechel, SG Withers - Accounts of chemical research, 2000 - ACS Publications
In order to accelerate the hydrolysis of glycosidic bonds by factors approaching 1017-fold,
glycosidases have evolved finely tuned active sites optimally configured for transition-state …

Glucosinolate structures in evolution

N Agerbirk, CE Olsen - Phytochemistry, 2012 - Elsevier
By 2000, around 106 natural glucosinolates (GSLs) were probably documented. In the past
decade, 26 additional natural GSL structures have been elucidated and documented …

Myrosinase: gene family evolution and herbivore defense in Brassicaceae

L Rask, E Andréasson, B Ekbom, S Eriksson… - Plant molecular …, 2000 - Springer
Glucosinolates are a category of secondary products present primarily in species of the
order Capparales. When tissue is damaged, for example by herbivory, glucosinolates are …

The enzymic and chemically induced decomposition of glucosinolates

AM Bones, JT Rossiter - Phytochemistry, 2006 - Elsevier
While the myrosinase–glucosinolate system has been reviewed in recent years by a number
of authors, little attention has been paid to the enzymic and non-enzymic degradation of …

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

DJ Vocadlo, GJ Davies, R Laine, SG Withers - Nature, 2001 - nature.com
Hen egg-white lysozyme (HEWL) was the first enzyme to have its three-dimensional
structure determined by X-ray diffraction techniques. A catalytic mechanism, featuring a long …