Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

Multiple sclerosis (MS) is an autoimmune demyelinating and neurodegenerative disease of
the central nervous system, and the leading cause of nontraumatic neurological disability in …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

A number of recent advances have been made in the clinical diagnosis and prognostication
of multiple sclerosis patients. Future research will enable the development of more accurate …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

An individualized innovative disease management is of great importance for people with
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …

Recent data suggest that multiple sclerosis white matter lesions surrounded by a rim of iron
containing microglia, termed iron rim lesions, signify patients with more severe disease …

The diagnosis of multiple sclerosis is based on neurological symptoms and signs, alongside
evidence of dissemination of CNS lesions in space and time. MRI is often sufficient to …

The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in
research and clinical practice. Scientific advances in the past 7 years suggest that they might …

Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF
aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains …