ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma

CG Barker, S Sharma, AM Santos, KS Nikolakopoulos… - bioRxiv, 2024 - biorxiv.org
Resistance to BRAF and MAPK inhibitors is a significant challenge in melanoma treatment,
driven by adaptive and acquired mechanisms that allow tumour cells to evade therapy …