Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters

M Del Giudice, SW Gangestad - Brain, behavior, and immunity, 2018 - Elsevier
Behavioral researchers have increasingly become interested in the idea that chronic, low-
grade inflammation is a pathway through which social and behavioral variables exert long …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

The behavioural constellation of deprivation: Causes and consequences

GV Pepper, D Nettle - Behavioral and Brain Sciences, 2017 - cambridge.org
Socioeconomic differences in behaviour are pervasive and well documented, but their
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …

Coronary atherosclerosis in indigenous South American Tsimane: a cross-sectional cohort study

H Kaplan, RC Thompson, BC Trumble, LS Wann… - The Lancet, 2017 - thelancet.com
Background Conventional coronary artery disease risk factors might potentially explain at
least 90% of the attributable risk of coronary artery disease. To better understand the …

Food insecurity as a driver of obesity in humans: The insurance hypothesis

D Nettle, C Andrews, M Bateson - Behavioral and Brain Sciences, 2017 - cambridge.org
Integrative explanations of why obesity is more prevalent in some sectors of the human
population than others are lacking. Here, we outline and evaluate one candidate …

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

S Horvath, M Gurven, ME Levine, BC Trumble… - Genome biology, 2016 - Springer
Background Epigenetic biomarkers of aging (the “epigenetic clock”) have the potential to
address puzzling findings surrounding mortality rates and incidence of cardio-metabolic …

Apolipoprotein-ε4 is associated with higher fecundity in a natural fertility population

BC Trumble, M Charifson, T Kraft, AR Garcia… - Science …, 2023 - science.org
In many populations, the a polipoprotein-ε 4 (APOE-ε 4) allele increases the risk for several
chronic diseases of aging, including dementia and cardiovascular disease; despite these …

Meta‐analysis of the difference of medians

S McGrath, H Sohn, R Steele, A Benedetti - Biometrical Journal, 2020 - Wiley Online Library
We consider the problem of meta‐analyzing two‐group studies that report the median of the
outcome. Often, these studies are excluded from meta‐analysis because there are no well …

Tradeoffs between immune function and childhood growth among Amazonian forager-horticulturalists

SS Urlacher, PT Ellison, LS Sugiyama… - Proceedings of the …, 2018 - National Acad Sciences
Immune function is an energetically costly physiological activity that potentially diverts
calories away from less immediately essential life tasks. Among develo** organisms, the …

The Tsimane health and life history project: integrating anthropology and biomedicine

M Gurven, J Stieglitz, B Trumble… - … : Issues, News, and …, 2017 - Wiley Online Library
Abstract The Tsimane Health and Life History Project, an integrated bio‐behavioral study of
the human life course, is designed to test competing hypotheses of human life‐history …