Unbiased spatial proteomics with single-cell resolution in tissues
Mass spectrometry (MS)-based proteomics has become a powerful technology to quantify
the entire complement of proteins in cells or tissues. Here, we review challenges and recent …
the entire complement of proteins in cells or tissues. Here, we review challenges and recent …
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation
Single‐cell technologies are revolutionizing biology but are today mainly limited to imaging
and deep sequencing. However, proteins are the main drivers of cellular function and in …
and deep sequencing. However, proteins are the main drivers of cellular function and in …
Deep topographic proteomics of a human brain tumour
The spatial organisation of cellular protein expression profiles within tissue determines
cellular function and is key to understanding disease pathology. To define molecular …
cellular function and is key to understanding disease pathology. To define molecular …
Graph neural networks learn emergent tissue properties from spatial molecular profiles
Tissue phenotypes such as metabolic states, inflammation, and tumor properties are
functions of molecular states of cells that constitute the tissue. Recent spatial molecular …
functions of molecular states of cells that constitute the tissue. Recent spatial molecular …
CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells
Motivation Cell–cell communications regulate internal cellular states, eg gene expression
and cell functions, and play pivotal roles in normal development and disease states …
and cell functions, and play pivotal roles in normal development and disease states …
On the pitfalls of deep image segmentation for lightsheet microscopy
Fluorescence light sheet microscopy (LSM) of tissue cleared samples enables holistic 3D
imaging of the human brain and the full murine body. While this novel imaging method …
imaging of the human brain and the full murine body. While this novel imaging method …
CIMT 2022: Report on the 19th Annual Meeting of the Association for Cancer Immunotherapy
PA Berger, J Freitag, SC Linkenbach… - Human Vaccines & …, 2022 - Taylor & Francis
ABSTRACT The 19th Annual Meeting of the Association for Cancer Immunotherapy (CIMT),
Europe's cancer immunotherapy meeting, was the first in-person event organized by CIMT …
Europe's cancer immunotherapy meeting, was the first in-person event organized by CIMT …
[PDF][PDF] Fluid Homeostasis in Neuroinflammation
M Ramos - 2022 - portal.research.lu.se
Maintaining fluid homeostasis is very important for brain health, partly because the
cerebrospinal fluid, which washes in and out, cleans the brain from accumulated waste. This …
cerebrospinal fluid, which washes in and out, cleans the brain from accumulated waste. This …
[CITATA][C] 179 Methods and Challenges of Tissue Clearing Engineering for Tissue Complexity 5
AH Nguyen, DH Tran, H Cao - Cutting-edge Technologies in Biological … - River Publishers