Anti-Müllerian hormone and ovarian reserve: update on assessing ovarian function

LME Moolhuijsen, JA Visser - The Journal of Clinical …, 2020 - academic.oup.com
Context Anti-müllerian hormone (AMH) is produced by granulosa cells of small, growing
follicles in the ovary. Serum AMH levels strongly correlate with the number of growing …

Anti-Müllerian hormone in pathogenesis, diagnostic and treatment of PCOS

E Rudnicka, M Kunicki, A Calik-Ksepka… - International journal of …, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-aged women. It is characterized by chronic anovulation, hyperandrogenism …

Evaluation of inflammation and follicle depletion during ovarian ageing in mice

C Lliberos, SH Liew, P Zareie, NL La Gruta… - Scientific Reports, 2021 - nature.com
Reproductive ageing in females is defined by a progressive decline in follicle number and
oocyte quality. This is a natural process that leads to the loss of fertility and ovarian function …

How is the number of primordial follicles in the ovarian reserve established?

JK Findlay, KJ Hutt, M Hickey… - Biology of …, 2015 - academic.oup.com
The number of primordial follicles in the ovarian reserve is an important determinant of the
length of the ovarian lifespan, and therefore the fertility of an individual. This reserve …

Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature …

P Igboeli, A El Andaloussi, U Sheikh, H Takala… - Journal of Medical Case …, 2020 - Springer
Background Premature ovarian failure is a relatively common condition that affects 1–3% of
adult women. Premature ovarian failure occurs when there is loss of ovarian function in …

The inflammasome contributes to depletion of the ovarian reserve during aging in mice

C Lliberos, SH Liew, A Mansell, KJ Hutt - Frontiers in Cell and …, 2021 - frontiersin.org
Ovarian aging is a natural process characterized by follicular depletion and a reduction in
oocyte quality, resulting in loss of ovarian function, cycle irregularity and eventually infertility …

Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats

MA Brieño-Enríquez, M Faykoo-Martinez… - Nature …, 2023 - nature.com
In the long-lived naked mole-rat (NMR), the entire process of oogenesis occurs postnatally.
Germ cell numbers increase significantly in NMRs between postnatal days 5 (P5) and P8 …

AMH as the primary marker for fertility

D Dewailly, J Laven - European journal of endocrinology, 2019 - academic.oup.com
In women, the anti-Müllerian hormone (AMH) is secreted by the granulosa cells of growing
follicles. Its measurement is strongly correlated with antral follicle count and represents a …

Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity

ME Tharp, S Malki, A Bortvin - Nature Communications, 2020 - nature.com
Female reproductive success critically depends on the size and quality of a finite ovarian
reserve. Paradoxically, mammals eliminate up to 80% of the initial oocyte pool through the …

Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve

MH Van den Berg, A Overbeek, CB Lambalk… - Human …, 2018 - academic.oup.com
STUDY QUESTION Which treatment-related factors are (dose-dependently) associated with
abnormal hormonal and ultrasound markers of ovarian reserve in female childhood cancer …