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A contextualized reinforcer pathology approach to addiction
Behavioural economic accounts of addiction conceptualize harmful drug use as an operant
reinforcer pathology, emphasizing that a drug is consumed because of overvaluation of …
reinforcer pathology, emphasizing that a drug is consumed because of overvaluation of …
Sex differences in opioid and psychostimulant craving and relapse: a critical review
A widely held dogma in the preclinical addiction field is that females are more vulnerable
than males to drug craving and relapse. Here, we first review clinical studies on sex …
than males to drug craving and relapse. Here, we first review clinical studies on sex …
Whole person recovery from substance use disorder: a call for research examining a dynamic behavioral ecological model of contexts supportive of recovery
Background Abstinence has long been considered the defining feature of recovery from
substance use disorder, with a focus on individual level factors associated with abstinence …
substance use disorder, with a focus on individual level factors associated with abstinence …
The protective effect of social reward on opioid and psychostimulant reward and relapse: behavior, pharmacology, and brain regions
Until recently, most modern neuroscience research on addiction using animal models did
not incorporate manipulations of social factors. Social factors play a critical role in human …
not incorporate manipulations of social factors. Social factors play a critical role in human …
An operant social self-administration and choice model in mice
Little is known about how social factors contribute to neurobiology or neuropsychiatric
disorders. The use of mice allows one to probe the neurobiological bases of social …
disorders. The use of mice allows one to probe the neurobiological bases of social …
Factors modulating the incubation of drug and non-drug craving and their clinical implications
It was suggested in 1986 that cue-induced cocaine craving increases progressively during
early abstinence and remains high during extended periods of time. Clinical evidence now …
early abstinence and remains high during extended periods of time. Clinical evidence now …
Defining social reward: A systematic review of human and animal studies.
Social rewards are strong drivers of behavior and fundamental to well-being, yet there is a
lack of consensus regarding what actually defines a reward as “social.” Because a …
lack of consensus regarding what actually defines a reward as “social.” Because a …
Is addiction a brain disease? A plea for agnosticism and heterogeneity
Rationale Although increasingly subject to criticism, the brain disease model of addiction
(BDMA) remains dominant within addiction science. Yet few advocates or critics of the …
(BDMA) remains dominant within addiction science. Yet few advocates or critics of the …
The relevance of animal models of social isolation and social motivation for understanding schizophrenia: review and future directions
SB Powell, NR Swerdlow - Schizophrenia Bulletin, 2023 - academic.oup.com
Abstract Background and Hypotheses Social dysfunction in schizophrenia includes
symptoms of withdrawal and deficits in social skills, social cognition, and social motivation …
symptoms of withdrawal and deficits in social skills, social cognition, and social motivation …
Characterization of operant social interaction in rats: effects of access duration, effort, peer familiarity, housing conditions, and choice between social interaction vs …
Rationale and objective Social factors play a critical role in drug addiction. We recently
showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self …
showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self …