Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

YH Peng, SK Hsiao, K Gupta, A Ruland… - Nature …, 2023 - nature.com
Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic
matrices. However, commonly used matrix materials lack control over key cell-instructive …

Putting DNA to work as generic polymeric materials

D Wang, P Liu, D Luo - Angewandte Chemie, 2022 - Wiley Online Library
DNA is a true polymer that stores the genetic information of an organism. With its amazing
biological and polymeric characteristics, DNA has been regarded as a universal building …

DNA hydrogels in the perspective of mechanical properties

D Cao, Y **e, J Song - Macromolecular Rapid Communications, 2022 - Wiley Online Library
Tailoring the mechanical properties has always been a key to the field of hydrogels in terms
of different applications. Particularly, DNA hydrogels offer an unambiguous way to precisely …

Programmable polymer materials empowered by DNA nanotechnology

SK Speed, K Gupta, YH Peng… - Journal of Polymer …, 2023 - Wiley Online Library
Over the past century, synthetic polymers have had a transformative impact on human life,
replacing nature‐derived materials in many areas. Yet, despite their many advantages, the …

Cellulose/collagen dressings for diabetic foot ulcer: A review

R Naomi, MB Fauzi - Pharmaceutics, 2020 - mdpi.com
Diabetic foot ulcer (DFU) is currently a global concern and it requires urgent attention, as the
cost allocation by the government for DFU increases every year. This review was performed …

DNA nanostructures in the fight against infectious diseases

DM Smith, A Keller - Advanced nanobiomed research, 2021 - Wiley Online Library
Throughout history, humanity has been threatened by countless epidemic and pandemic
outbreaks of infectious diseases, from the Justinianic Plague to the Spanish flu to COVID …

Characterization of binding interactions of SARS-CoV-2 spike protein and DNA-peptide nanostructures

M Kruse, B Altattan, EM Laux, N Grasse, L Heinig… - Scientific Reports, 2022 - nature.com
Binding interactions of the spike proteins of the severe acute respiratory syndrome corona
virus 2 (SARS-CoV-2) to a peptide fragment derived from the human angiotensin converting …

Integration of functional peptides into nucleic acid-based nanostructures

JS Freitag, C Möser, R Belay, B Altattan, N Grasse… - Nanoscale, 2023 - pubs.rsc.org
In many applications such as diagnostics and therapy development, small peptide fragments
consisting of only a few amino acids are often attractive alternatives to bulky proteins. This is …

Heavy water induces bundling in entangled actin networks

P Mollenkopf, D Prascevic, TM Bayerl, JA Käs… - RSC …, 2023 - pubs.rsc.org
Heavy water is known to affect many different biological systems, with the most striking
effects observed at the cellular level. Many dynamic processes, such as migration or …

Differences in cortical contractile properties between healthy epithelial and cancerous mesenchymal breast cells

E Warmt, S Grosser, E Blauth, X **e… - New Journal of …, 2021 - iopscience.iop.org
Cell contractility is mainly imagined as a force dipole-like interaction based on actin stress
fibers that pull on cellular adhesion sites. Here, we present a different type of contractility …