Structural and functional evolution of the translocator protein (18 kDa)

J Fan, P Lindemann, M GJ Feuilloley… - Current molecular …, 2012 - ingentaconnect.com
Translocator proteins (TSPO) are the products of a family of genes that is evolutionarily
conserved from bacteria to humans and expressed in most mammalian tissues and cells …

TSPO protein binding partners in bacteria, animals, and plants

C Hiser, BL Montgomery, S Ferguson-Miller - Journal of Bioenergetics and …, 2021 - Springer
The ancient membrane protein TSPO is phylogenetically widespread from archaea and
bacteria to insects, vertebrates, plants, and fungi. TSPO's primary amino acid sequence is …

The Arabidopsis Multistress Regulator TSPO Is a Heme Binding Membrane Protein and a Potential Scavenger of Porphyrins via an Autophagy-Dependent …

C Vanhee, G Zapotoczny, D Masquelier… - The Plant …, 2011 - academic.oup.com
TSPO, a stress-induced, posttranslationally regulated, early secretory pathway-localized
plant cell membrane protein, belongs to the TspO/MBR family of regulatory proteins, which …

Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis

J Fan, MB Rone, V Papadopoulos - Journal of Biological Chemistry, 2009 - jbc.org
Translocator protein (TSPO) is an 18-kDa cholesterol-and drug-binding protein conserved
from bacteria to humans. While surveying for Tspo-like genes, we identified its paralogous …

Enigmatic Translocator protein (TSPO) and cellular stress regulation

H Batoko, V Veljanovski, P Jurkiewicz - Trends in biochemical sciences, 2015 - cell.com
Translocator proteins (TSPOs) are conserved, ubiquitous membrane proteins identified
initially as benzodiazepine-binding proteins in mammalian cells. Recent genetic and …

A novel interaction of translocator protein 18 kDa (TSPO) with NADPH oxidase in microglia

MK Loth, SR Guariglia, DB Re, J Perez… - Molecular …, 2020 - Springer
In the brain neuropil, translocator protein 18 kDa (TSPO) is a stress response protein that is
upregulated in microglia and astrocytes in diverse central nervous system pathologies …

[HTML][HTML] Mitochondrial translocator protein (TSPO) function is not essential for heme biosynthesis

AH Zhao, LN Tu, C Mukai, MP Sirivelu, VV Pillai… - Journal of Biological …, 2016 - Elsevier
Function of the mammalian translocator protein (TSPO; previously known as the peripheral
benzodiazepine receptor) remains unclear because its presumed role in steroidogenesis …

Yolk sac endoderm is the major source of serum proteins and lipids and is involved in the regulation of vascular integrity in early chick development

F Nakazawa, C Alev, LM Jakt… - Developmental …, 2011 - Wiley Online Library
An important function of the vascular system is nutrient delivery. In adult animals, this is
mediated through a close contact of the mesoderm‐derived vasculature with the endoderm …

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood

I Marginedas-Freixa, C Hattab, G Bouyer, F Halle… - Scientific reports, 2016 - nature.com
After invading red blood cells (RBCs), Plasmodium falciparum (Pf) can export its own
proteins to the host membrane and activate endogenous channels that are present in the …

Genomic organization of zebra finch alpha and beta globin genes and their expression in primitive and definitive blood in comparison with globins in chicken

C Alev, K Shinmyozu, BAS McIntyre… - Development Genes and …, 2009 - Springer
How alpha and beta globin genes are organized and expressed in amniotes is of interest to
researchers in a wide variety of fields. Data regarding this from avian species have been …