Glycoconjugates: synthesis, functional studies, and therapeutic developments

SS Shivatare, VS Shivatare, CH Wong - Chemical reviews, 2022 - ACS Publications
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Functions of cell surface heparan sulfate proteoglycans

M Bernfield, M Götte, PW Park, O Reizes… - Annual review of …, 1999 - annualreviews.org
▪ Abstract The heparan sulfate on the surface of all adherent cells modulates the actions of a
large number of extracellular ligands. Members of both cell surface heparan sulfate …

[HTML][HTML] The extracellular matrix in development and morphogenesis: a dynamic view

T Rozario, DW DeSimone - Developmental biology, 2010 - Elsevier
The extracellular matrix (ECM) is synthesized and secreted by embryonic cells beginning at
the earliest stages of development. Our understanding of ECM composition, structure and …

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

M Presta, P Dell'Era, S Mitola, E Moroni… - Cytokine & growth factor …, 2005 - Elsevier
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …

Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

T Kondo, T Setoguchi, T Taga - Proceedings of the National …, 2004 - National Acad Sciences
Both stem cells and cancer cells are thought to be capable of unlimited proliferation.
Paradoxically, however, some cancers seem to contain stem-like cells (cancer stem cells) …

Biological roles of fibroblast growth factor-2

A Bikfalvi, S Klein, G Pintucci, DB Rifkin - Endocrine reviews, 1997 - academic.oup.com
Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
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Growth factors in the extracellular matrix

J Taipale, J Keski‐Oja - The FASEB Journal, 1997 - Wiley Online Library
Much recent research has focused on the study of the expression of growth factor genes and
on the identification of growth factor signaling mechanisms inside cells. However, growth …

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

S Bellusci, J Grindley, H Emoto, N Itoh… - …, 1997 - journals.biologists.com
During mouse lung morphogenesis, the distal mesenchyme regulates the growth and
branching of adjacent endoderm. We report here that fibroblast growth factor 10 (Fgf10) is …

Distinct neural stem cells proliferate in response to EGF and FGF in the develo** mouse telencephalon

V Tropepe, M Sibilia, BG Ciruna, J Rossant… - Developmental …, 1999 - Elsevier
Multipotent, self-renewing neural stem cells reside in the embryonic mouse telencephalic
germinal zone. Using anin vitroneurosphere assay for neural stem cell proliferation, we …

Proteoglycans in the develo** brain: new conceptual insights for old proteins

CE Bandtlow, DR Zimmermann - Physiological reviews, 2000 - journals.physiology.org
Proteoglycans are a heterogeneous class of proteins bearing sulfated glycosaminoglycans.
Some of the proteoglycans have distinct core protein structures, and others display …