Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …

[HTML][HTML] The disease burden of influenza beyond respiratory illness

AE Macias, JE McElhaney, SS Chaves, J Nealon… - Vaccine, 2021 - Elsevier
Although influenza is primarily considered a respiratory infection and causes significant
respiratory mortality, evidence suggests that influenza has an additional burden due to …

[HTML][HTML] Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

S Ramakrishnan, DV Nicolau, B Langford… - The Lancet …, 2021 - thelancet.com
Background Multiple early reports of patients admitted to hospital with COVID-19 showed
that patients with chronic respiratory disease were significantly under-represented in these …

Characterizing long COVID in children and adolescents

RS Gross, T Thaweethai, LC Kleinman, JN Snowden… - JAMA, 2024 - jamanetwork.com
Importance Most research to understand postacute sequelae of SARS-CoV-2 infection
(PASC), or long COVID, has focused on adults, with less known about this complex …

Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis

KE Lafond, RM Porter, MJ Whaley, Z Suizan… - PLoS …, 2021 - journals.plos.org
Background Influenza illness burden is substantial, particularly among young children, older
adults, and those with underlying conditions. Initiatives are underway to develop better …

Exacerbations of COPD

C Viniol, CF Vogelmeier - European Respiratory Review, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer …

The lung microbiome, immunity, and the pathogenesis of chronic lung disease

DN O'Dwyer, RP Dickson, BB Moore - The journal of immunology, 2016 - journals.aai.org
The development of culture-independent techniques for microbiological analysis has
uncovered the previously unappreciated complexity of the bacterial microbiome at various …

Human rhinoviruses

SE Jacobs, DM Lamson, K St. George… - Clinical microbiology …, 2013 - Am Soc Microbiol
Human rhinoviruses (HRVs), first discovered in the 1950s, are responsible for more than
one-half of cold-like illnesses and cost billions of dollars annually in medical visits and …

The role of the microbiome in exacerbations of chronic lung diseases

RP Dickson, FJ Martinez, GB Huffnagle - The Lancet, 2014 - thelancet.com
Culture-independent microbiological techniques have shown a previously unappreciated
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …

Guidelines for the management of adult lower respiratory tract infections‐Full version

M Woodhead, F Blasi, S Ewig, J Garau… - Clinical microbiology …, 2011 - Wiley Online Library
Clin Microbiol Infect 2011; 17 (Suppl. 6): E1–E59 Abstract This document is an update of
Guidelines published in 2005 and now includes scientific publications through to May 2010 …