Tumor angiogenesis: causes, consequences, challenges and opportunities
R Lugano, M Ramachandran, A Dimberg - Cellular and Molecular Life …, 2020 - Springer
Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …
vary between tumor type and anatomic location, but also occur simultaneously within the …
Role of CD93 in Health and Disease
CD93 (also known as complement protein 1 q subcomponent receptor C1qR1 or C1qRp), is
a transmembrane glycoprotein encoded by a gene located on 20p11. 21 and composed of …
a transmembrane glycoprotein encoded by a gene located on 20p11. 21 and composed of …
Single-cell RNA sequencing of lymph node stromal cells reveals niche-associated heterogeneity
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the
immune response. However, the full diversity of lymph node (LN) SCs remains undefined …
immune response. However, the full diversity of lymph node (LN) SCs remains undefined …
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy
The immature and dysfunctional vascular network within solid tumors poses a substantial
obstacle to immunotherapy because it creates a hypoxic tumor microenvironment that …
obstacle to immunotherapy because it creates a hypoxic tumor microenvironment that …
A review of anti-angiogenic targets for monoclonal antibody cancer therapy
DH Kong, MR Kim, JH Jang, HJ Na, S Lee - International journal of …, 2017 - mdpi.com
Tumor angiogenesis is a key event that governs tumor progression and metastasis. It is
controlled by the complicated and coordinated actions of pro-angiogenic factors and their …
controlled by the complicated and coordinated actions of pro-angiogenic factors and their …
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis
R Lugano, K Vemuri, D Yu, M Bergqvist… - The Journal of …, 2018 - Am Soc Clin Investig
Tumor angiogenesis occurs through regulation of genes that orchestrate endothelial
sprouting and vessel maturation, including deposition of a vessel-associated extracellular …
sprouting and vessel maturation, including deposition of a vessel-associated extracellular …
The dual role of mesenchymal stem cells in cancer pathophysiology: pro-tumorigenic effects versus therapeutic potential
Y Slama, F Ah-Pine, M Khettab, A Arcambal… - International Journal of …, 2023 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells involved in numerous
physiological events, including organogenesis, the maintenance of tissue homeostasis …
physiological events, including organogenesis, the maintenance of tissue homeostasis …
C‐type lectin domain group 14 proteins in vascular biology, cancer and inflammation
The C‐type lectin domain (CTLD) group 14 family of transmembrane glycoproteins consist of
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …
CD248 regulates Wnt signaling in pericytes to promote angiogenesis and tumor growth in lung cancer
CL Hong, IS Yu, CH Pai, JS Chen, MS Hsieh, HL Wu… - Cancer Research, 2022 - AACR
The tumor microenvironment plays a central role in cancer initiation and progression.
CD248 is expressed in tumor-associated stromal cells, particularly fibroblasts and pericytes …
CD248 is expressed in tumor-associated stromal cells, particularly fibroblasts and pericytes …
Dual‐Functional Nanodroplet for Tumor Vasculature Ultrasound Imaging and Tumor Immunosuppressive Microenvironment Remodeling
Y Liang, S Zhang, D Wang, P Ji… - Advanced …, 2024 - Wiley Online Library
Accurately evaluating tumor neoangiogenesis and conducting precise interventions toward
an immune‐favorable microenvironment are of significant clinical importance. In this study, a …
an immune‐favorable microenvironment are of significant clinical importance. In this study, a …