Background Methodological studies–studies that evaluate the design, analysis or reporting
of other research-related reports–play an important role in health research. They help to …

The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's
disease, and as such identification of entorhinal cortex dysfunction may aid detection of the …

Background In modern urban environments children have a high incidence of inflammatory
disorders, including allergies, asthma, and type 1 diabetes. The underlying cause of these …

Urbanization reduces microbiological abundance and diversity, which has been associated
with immune mediated diseases. Urban greening may be used as a prophylactic method to …

Brain somatic mutations in various components of the mTOR complex 1 (mTORC1) pathway
have emerged as major causes of focal malformations of cortical development and …

Exposure to aminoglycoside antibiotics can lead to the generation of toxic levels of reactive
oxygen species (ROS) within mechanosensory hair cells of the inner ear that have been …

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a negative
regulator of AKT/mTOR signaling pathway. Mutations in PTEN are found in patients with …

Introduction. Amhara region has one of the highest rates of female child early marriage in
Ethiopia, with eighty percent of girls in the region being married at the age of eighteen …

We developed a new method to link designer emotions with corresponding designer
activities while using computer-aided design (cad) software. Our method employs …

Hyperactivation of PI3K/PTEN-mTOR signaling during neural development is associated
with focal cortical dysplasia (FCD), autism, and epilepsy. mTOR can signal through two …