Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization
Polypeptides have the same or similar backbone structures as proteins and peptides,
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …
Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides
A great hurdle in the production of synthetic polypeptides lies in the access of N-
carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe …
carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe …
Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications
Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …
century ago, it was only recently that pSar gained broader attention and is considered a …
Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that
have found broad biomedical applications. Ring-opening polymerization of N …
have found broad biomedical applications. Ring-opening polymerization of N …
Water‐insensitive synthesis of poly‐β‐peptides with defined architecture
Biocompatible and proteolysis‐resistant poly‐β‐peptides have broad applications and are
dominantly synthesized via the harsh and water‐sensitive ring‐opening polymerization of β …
dominantly synthesized via the harsh and water‐sensitive ring‐opening polymerization of β …
Synthetic peptide branched polymers for antibacterial and biomedical applications
Antimicrobial resistance is a major threat to human health, and this 'invisible pandemic'is a
looming public health crisis. Accordingly, both broad-spectrum and selective antimicrobial …
looming public health crisis. Accordingly, both broad-spectrum and selective antimicrobial …
Biodegradable polysarcosine with inserted alanine residues: Synthesis and enzymolysis
P Zhou, T Shen, W Chen, J Sun, J Ling - Biomacromolecules, 2022 - ACS Publications
Polysarcosine (PSar), a water-soluble polypeptoid, is gifted with biodegradability via the
random ring-opening copolymerization of sarcosine-and alanine-N-thiocarboxyanhydrides …
random ring-opening copolymerization of sarcosine-and alanine-N-thiocarboxyanhydrides …
Biological applications of water-soluble polypeptides with ordered secondary structures
Water-soluble polypeptides are a class of synthetic polymers with peptide bond frameworks
imitating natural proteins and have broad prospects in biological applications. The …
imitating natural proteins and have broad prospects in biological applications. The …
Oxidation-sensitive polymersomes based on amphiphilic diblock copolypeptoids
Stimuli-responsive polymersomes formed by amphiphilic block copolymers have attracted
substantial attention as smart and robust containers for drug delivery and …
substantial attention as smart and robust containers for drug delivery and …