Environmental and human risk assessment of polymer nanocarriers: a review on current analytical challenges and promising approaches

DMM Das, J Travas-Sejdic, E Leitao… - Environmental Science …, 2025 - pubs.rsc.org
Polymer nanocarriers (PNCs) are designed to deliver active ingredients in pharmaceuticals,
food science and agricultural applications and it is essential to ensure their safety towards …

Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines

M Puccetti, M Pariano, A Schoubben… - Journal of Pharmacy …, 2024 - academic.oup.com
Biological membrane-engineered lipid nanoparticles (LNP) have shown enormous potential
as vehicles for drug delivery due to their outstanding biomimetic properties. To make these …

Targeted drug delivery using a plug-to-direct antibody–nanogel conjugate

U Huynh, P Wu, J Qiu, T Prachyathipsakul… - …, 2023 - ACS Publications
Targeted drug delivery using antibody–drug conjugates has attracted great attention due to
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …

Suborgan Level Quantitation of Proteins in Tissues Delivered by Polymeric Nanocarriers

DK Agrohia, R Goswami, T Jantarat, YA Çiçek… - ACS …, 2024 - ACS Publications
Amidst the rapid growth of protein therapeutics as a drug class, there is an increased focus
on designing systems to effectively deliver proteins to target organs. Quantitative monitoring …

Optimizing Conjugation Chemistry, Antibody Conjugation Site, and Surface Density in Antibody–Nanogel Conjugates (ANCs) for Cell-Specific Drug Delivery

P Wu, T Prachyathipsakul, U Huynh, J Qiu… - Bioconjugate …, 2023 - ACS Publications
Targeted delivery of therapeutics using antibody–nanogel conjugates (ANCs) with a high
drug-to-antibody ratio has the potential to overcome some of the inherent limitations of …

Multiplexed Quantitative Screening of the Cellular Uptake of Proteins Delivered by Polymeric Nanocarriers

DK Agrohia, R Goswami, YA Çiçek… - Analytical …, 2024 - ACS Publications
Proteins are important therapeutic agents, yet better methods are needed to deliver them
inside of cells. Polymeric nanocarriers (PNCs) are versatile materials for this purpose, and to …

The evolution of immune profiling: will there be a role for nanoparticles?

OE Eremina, C Vazquez, KN Larson… - Nanoscale …, 2024 - pubs.rsc.org
Immune profiling provides insights into the functioning of the immune system, including the
distribution, abundance, and activity of immune cells. This understanding is essential for …

Quantitative imaging of the sub-organ distributions of nanomaterials in biological tissues via laser ablation inductively coupled plasma mass spectrometry

T Jantarat, JD Lauterbach, J Doungchawee… - Analyst, 2023 - pubs.rsc.org
Nanomaterials have been employed in many biomedical applications, and their distributions
in biological systems can provide an understanding of their behavior in vivo. Laser ablation …

DEVELOPMENT OF BIOMOLECULE NANOPARTICLE CONJUGATE FOR TARGETED DELIVERY OF THERAPEUTICS

P Wu - 2023 - scholarworks.umass.edu
Delivery of therapeutics specifically to the disease site is the final goal for the field of drug
discovery. Considerable efforts in understanding disease biology have contributed to …