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Environmental and human risk assessment of polymer nanocarriers: a review on current analytical challenges and promising approaches
DMM Das, J Travas-Sejdic, E Leitao… - Environmental Science …, 2025 - pubs.rsc.org
Polymer nanocarriers (PNCs) are designed to deliver active ingredients in pharmaceuticals,
food science and agricultural applications and it is essential to ensure their safety towards …
food science and agricultural applications and it is essential to ensure their safety towards …
Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines
M Puccetti, M Pariano, A Schoubben… - Journal of Pharmacy …, 2024 - academic.oup.com
Biological membrane-engineered lipid nanoparticles (LNP) have shown enormous potential
as vehicles for drug delivery due to their outstanding biomimetic properties. To make these …
as vehicles for drug delivery due to their outstanding biomimetic properties. To make these …
Targeted drug delivery using a plug-to-direct antibody–nanogel conjugate
Targeted drug delivery using antibody–drug conjugates has attracted great attention due to
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …
Suborgan Level Quantitation of Proteins in Tissues Delivered by Polymeric Nanocarriers
Amidst the rapid growth of protein therapeutics as a drug class, there is an increased focus
on designing systems to effectively deliver proteins to target organs. Quantitative monitoring …
on designing systems to effectively deliver proteins to target organs. Quantitative monitoring …
Optimizing Conjugation Chemistry, Antibody Conjugation Site, and Surface Density in Antibody–Nanogel Conjugates (ANCs) for Cell-Specific Drug Delivery
Targeted delivery of therapeutics using antibody–nanogel conjugates (ANCs) with a high
drug-to-antibody ratio has the potential to overcome some of the inherent limitations of …
drug-to-antibody ratio has the potential to overcome some of the inherent limitations of …
Multiplexed Quantitative Screening of the Cellular Uptake of Proteins Delivered by Polymeric Nanocarriers
DK Agrohia, R Goswami, YA Çiçek… - Analytical …, 2024 - ACS Publications
Proteins are important therapeutic agents, yet better methods are needed to deliver them
inside of cells. Polymeric nanocarriers (PNCs) are versatile materials for this purpose, and to …
inside of cells. Polymeric nanocarriers (PNCs) are versatile materials for this purpose, and to …
The evolution of immune profiling: will there be a role for nanoparticles?
OE Eremina, C Vazquez, KN Larson… - Nanoscale …, 2024 - pubs.rsc.org
Immune profiling provides insights into the functioning of the immune system, including the
distribution, abundance, and activity of immune cells. This understanding is essential for …
distribution, abundance, and activity of immune cells. This understanding is essential for …
Quantitative imaging of the sub-organ distributions of nanomaterials in biological tissues via laser ablation inductively coupled plasma mass spectrometry
Nanomaterials have been employed in many biomedical applications, and their distributions
in biological systems can provide an understanding of their behavior in vivo. Laser ablation …
in biological systems can provide an understanding of their behavior in vivo. Laser ablation …
DEVELOPMENT OF BIOMOLECULE NANOPARTICLE CONJUGATE FOR TARGETED DELIVERY OF THERAPEUTICS
P Wu - 2023 - scholarworks.umass.edu
Delivery of therapeutics specifically to the disease site is the final goal for the field of drug
discovery. Considerable efforts in understanding disease biology have contributed to …
discovery. Considerable efforts in understanding disease biology have contributed to …