ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[HTML][HTML] Recent developments in multimodality fluorescence imaging probes

J Zhao, J Chen, S Ma, Q Liu, L Huang, X Chen… - … Pharmaceutica Sinica B, 2018 - Elsevier
Multimodality optical imaging probes have emerged as powerful tools that improve detection
sensitivity and accuracy, important in disease diagnosis and treatment. In this review, we …

In vivo imaging with antibodies and engineered fragments

AC Freise, AM Wu - Molecular immunology, 2015 - Elsevier
Antibodies have clearly demonstrated their utility as therapeutics, providing highly selective
and effective drugs to treat diseases in oncology, hematology, cardiology, immunology and …

Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery

Y Sun, X Zeng, Y **ao, C Liu, H Zhu, H Zhou… - Chemical …, 2018 - pubs.rsc.org
Accurate tumor identification is essential in cancer management. Incomplete excision of
tumor tissue, however, negatively affects the prognosis of the patient. To accomplish radical …

Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making

P Debie, S Hernot - Frontiers in Pharmacology, 2019 - frontiersin.org
Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent

KLS Chatalic, S Heskamp, M Konijnenberg… - …, 2016 - pmc.ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) is a well-established target for nuclear imaging
and therapy of prostate cancer (PCa). Radiolabeled small-molecule PSMA inhibitors are …

PSMA-11–derived dual-labeled PSMA inhibitors for preoperative PET imaging and precise fluorescence-guided surgery of prostate cancer

AC Baranski, M Schäfer, U Bauder-Wüst… - Journal of Nuclear …, 2018 - jnm.snmjournals.org
Resection of tumors using targeted dual-modality probes combining preoperative imaging
with intraoperative guidance is of high clinical relevance and might considerably affect the …

Synthesis and preclinical characterization of the PSMA-targeted hybrid tracer PSMA-I&F for nuclear and fluorescence imaging of prostate cancer

M Schottelius, A Wurzer, K Wissmiller… - Journal of Nuclear …, 2019 - jnm.snmjournals.org
The prostate-specific membrane antigen (PSMA)–targeted radiotracers 68Ga/177Lu-PSMA-
I&T and 99mTc-PSMA-I&S (for i maging and s urgery) are currently successfully used for …

The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease

JC Evans, M Malhotra, JF Cryan… - British journal of …, 2016 - Wiley Online Library
Prostate specific membrane antigen (PSMA) otherwise known as glutamate
carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in …

Cyanine conjugate‐based biomedical imaging probes

Y Li, Y Zhou, X Yue, Z Dai - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …