[HTML][HTML] Copper-mediated living radical polymerization (atom transfer radical polymerization and copper (0) mediated polymerization): from fundamentals to …

C Boyer, NA Corrigan, K Jung, D Nguyen… - Chemical …, 2016 - ACS Publications
The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …

Esca** the endosome: assessing cellular trafficking mechanisms of non-viral vehicles

E Xu, WM Saltzman, AS Piotrowski-Daspit - Journal of Controlled Release, 2021 - Elsevier
Non-viral vehicles hold therapeutic promise in advancing the delivery of a variety of cargos
in vitro and in vivo, including small molecule drugs, biologics, and especially nucleic acids …

Visible‐Light‐Triggered Drug Release from TiO2 Nanotube Arrays: A Controllable Antibacterial Platform

J Xu, X Zhou, Z Gao, YY Song… - Angewandte Chemie …, 2016 - Wiley Online Library
In this work, we use a double‐layered stack of TiO2 nanotubes (TiNTs) to construct a visible‐
light‐triggered drug delivery system. The key for visible light drug release is a hydrophobic …

Near-infrared light-activated photochemical internalization of reduction-responsive polyprodrug vesicles for synergistic photodynamic therapy and chemotherapy

K Zhu, G Liu, J Hu, S Liu - Biomacromolecules, 2017 - ACS Publications
The use of intracellular reductive microenvironment to control the release of therapeutic
payloads has emerged as a popular approach to design and fabricate intelligent …

Coumarin-appended phosphorescent cyclometalated iridium (iii) complexes as mitochondria-targeted theranostic anticancer agents

RR Ye, CP Tan, LN Ji, ZW Mao - Dalton Transactions, 2016 - pubs.rsc.org
Theranostic anticancer agents incorporating anticancer properties with capabilities for real-
time treatment assessment are appealing candidates for chemotherapy. The design of …

Stimuli-responsive block copolymer-based assemblies for cargo delivery and theranostic applications

J Yin, Y Chen, ZH Zhang, X Han - Polymers, 2016 - mdpi.com
Although a number of tactics towards the fabrication and biomedical exploration of stimuli-
responsive polymeric assemblies being responsive and adaptive to various factors have …

Design and synthesis of multi-target directed 1, 2, 3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease

H Karimi Askarani, A Iraji, A Rastegari… - BMC chemistry, 2020 - Springer
To discover multifunctional agents for the treatment of Alzheimer's disease (AD), a new
series of 1, 2, 3-triazole-chromenone derivatives were designed and synthesized based on …

Lysosome-targeted iridium (III) compounds with pyridine-triphenylamine Schiff base ligands: Syntheses, antitumor applications and mechanisms

S Chen, X Liu, X Ge, Q Wang, Y **e, Y Hao… - Inorganic Chemistry …, 2020 - pubs.rsc.org
Six N-phenylcarbazole/triphenylamine modified half-sandwiched iridium (III) Schiff base
compounds ([(η5-Cpx) Ir (N^ N) Cl] PF6) were synthesised and characterised in this study …

In vitro and in vivo of triphenylamine-appended fluorescent half-sandwich iridium (iii) thiosemicarbazones antitumor complexes

M Shao, M Yao, X Liu, C Gao, W Liu, J Guo… - Inorganic …, 2021 - ACS Publications
Half-sandwiched structure iridium (III) complexes appear to be an attractive organometallic
antitumor agents in recent years. Here, four triphenylamine-modified fluorescent half …

Controlling and monitoring intracellular delivery of anticancer polymer nanomedicines

C Battistella, HA Klok - Macromolecular bioscience, 2017 - Wiley Online Library
Polymer nanomedicines are very attractive to improve the delivery of chemotherapeutics.
Polymer conjugates and other polymer‐based nanocarriers allow to increase plasma half …