Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …

Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally
affects individuals with obesity. The mechanisms by which obesity leads to the onset and …

Osteoarthritis (OA) is a common degenerative disease in mammals. However, its
pathogenesis remains unclear. Studies indicate that OA is not only an aging process that but …

Inflammatory changes are observed in affected joints of osteoarthritis (OA) patients and are
thought to be involved in the pathology that develops along OA progression. This narrative …

Osteoarthritis (OA) is a prevalent progressive disease that frequently coexists with obesity.
For several decades, OA was thought to be the result of ageing and mechanical stress on …

Osteoarthritis (OA) is a multifactorial joint disease characterized by degeneration of articular
cartilage, which leads to joints pain, disability and reduced quality of life in patients with OA …

Osteoarthritis (OA) is a chronic joint disease characterized by cartilage degradation,
osteophyte formation, subchondral bone sclerosis, and synovitis. Systemic factors such as …

Obesity is a well-known primary risk factor for osteoarthritis (OA). In recent decades, the
biomechanics-based theoretical paradigm for the pathogenesis of obesity-associated OA …