[HTML][HTML] Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes

S Gurunathan, MH Kang, M Jeyaraj, M Qasim, JH Kim - Cells, 2019 - mdpi.com
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …

[HTML][HTML] Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

Hypoxia induced changes of exosome cargo and subsequent biological effects

H Jiang, H Zhao, M Zhang, Y He, X Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Exosomes are small extracellular vesicles that are secreted by almost all types of cells and
exist in almost all extracellular spaces. As an important mediator of intercellular …

Chemically engineering cells for precision medicine

Y Wang, Z Li, F Mo, TJ Chen-Mayfield, A Saini… - Chemical Society …, 2023 - pubs.rsc.org
Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Advances on liver cell‐derived exosomes in liver diseases

Y Jiao, P Xu, H Shi, D Chen… - Journal of cellular and …, 2021 - Wiley Online Library
Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm, which
contain several donor cell‐associated proteins as well as mRNA, miRNA, and lipids and …

Extracellular vesicles from the microalga Tetraselmis chuii are biocompatible and exhibit unique bone tropism along with antioxidant and anti-inflammatory properties

G Adamo, P Santonicola, S Picciotto… - Communications …, 2024 - nature.com
Extracellular vesicles (EVs) are membrane-enclosed bio-nanoparticles secreted by cells
and naturally evolved to transport various bioactive molecules between cells and even …

Endothelial extracellular vesicles: from keepers of health to messengers of disease

A Mathiesen, T Hamilton, N Carter, M Brown… - International journal of …, 2021 - mdpi.com
Endothelium has a rich vesicular network that allows the exchange of macromolecules
between blood and parenchymal cells. This feature of endothelial cells, along with their …

Differential intracellular trafficking of extracellular vesicles in microglia and astrocytes

M Pantazopoulou, A Lamprokostopoulou… - Cellular and Molecular …, 2023 - Springer
Extracellular vesicles (EVs) have emerged as key players in cell-to-cell communication in
both physiological and pathological processes in the Central Nervous System. Thus far, the …

Transmission of NLRP3-IL-1β signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to adjacent neuron and endothelial cells via IL-1β/IL-1R1/TRAF6

J Pan, J Peng, X Li, H Wang, X Rong, Y Peng - Molecular Neurobiology, 2023 - Springer
The pyrin domain-containing protein 3 (NLRP3) inflammasome drives the profound cerebral
ischemia and reperfusion injury (I/R) and mediates the secretion of IL-1β (interleukin-1β) …

[HTML][HTML] Extracellular vesicles in neurodegenerative diseases: An update

S Sigdel, S Swenson, J Wang - International Journal of Molecular …, 2023 - mdpi.com
Neurodegenerative diseases affect millions of people worldwide. The likelihood of
develo** a neurodegenerative disease rises dramatically as life expectancy increases …