Develo** therapeutic approaches for twenty-first-century emerging infectious viral diseases

RM Meganck, RS Baric - Nature medicine, 2021‏ - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …

Risks of infectious disease in xenotransplantation

JA Fishman - New England Journal of Medicine, 2022‏ - Mass Medical Soc
Risks of Infectious Disease in Xenotransplantation | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda… - Science, 2020‏ - science.org
The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice

DR Martinez, A Schäfer, SR Leist, G De la Cruz, A West… - Science, 2021‏ - science.org
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …

The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses

DR Martinez, FR Moreira, NJ Catanzaro… - Science translational …, 2024‏ - science.org
Despite the wide availability of several safe and effective vaccines that prevent severe
COVID-19, the persistent emergence of severe acute respiratory syndrome coronavirus 2 …

The taxonomy, host range and pathogenicity of coronaviruses and other viruses in the Nidovirales order

Z Zhou, Y Qiu, X Ge - Animal Diseases, 2021‏ - Springer
The frequent emergence of coronavirus (CoV) epidemics has seriously threatened public
health and stock farming. The major hosts for CoVs are birds and mammals. Although most …

Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms

JM Flynn, N Samant, G Schneider-Nachum, DT Barkan… - Elife, 2022‏ - elifesciences.org
With the continual evolution of new strains of severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) that are more virulent, transmissible, and able to evade current vaccines …

Animal models of Long Covid: A hit-and-run disease

A Schäfer, SR Leist, JM Powers, RS Baric - Science Translational …, 2024‏ - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic has caused
more than 7 million deaths globally. Despite the presence of infection-and vaccine-induced …

Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis

Q Liu, HY Wang - Veterinary Research Communications, 2021‏ - Springer
The recent prevalence of coronavirus (CoV) poses a serious threat to animal and human
health. Currently, porcine enteric coronaviruses (PECs), including the transmissible …

Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions

AR Shiakolas, KJ Kramer, D Wrapp, SI Richardson… - Cell Reports …, 2021‏ - cell.com
The continual emergence of novel coronaviruses (CoV), such as severe acute respiratory
syndrome-(SARS)-CoV-2, highlights the critical need for broadly reactive therapeutics and …