Interpreting channel behavior in patches requires an understanding of patch structure and
dynamics, especially in studies of mechanosensitive channels. High resolution optical …

Like many other organisms, plants are capable of sensing and responding to mechanical
stimuli such as touch, osmotic pressure, and gravity. One mechanism for the perception of …

All excitable cell functions rely upon ion channels that are embedded in their plasma
membrane. Perturbations of ion channel structure or function result in pathologies ranging …

NMDA receptors have been shown to contribute to glutamate‐evoked currents in
oligodendrocytes. Activation of these receptors damages myelin in ischaemia, in part …

The identity and forms of activating ligands for ion channels are fundamental to their
physiological roles in rapid electrical signaling. P2X receptor channels are ATP-activated …

A robust platform providing a fluid lipid bilayer is in great demand not only for specific basic
research on membrane proteins, but also for related applications. Here we present …

We developed a new, simple and robust approach for rapid screening of single molecule
interactions with protein channels. Our glass nanopipets can be fabricated simply by …

The psyllid B actericera trigonica H odkinson (H emiptera: T riozidae) is a carrot and celery
pest recently described as a vector of the plant pathogenic bacterium C andidatus …

Ethanol modulation of calcium-and voltage-gated potassium (slo1) channels alters neuronal
excitability, cerebrovascular tone, brain function, and behavior, yet the mechanism of this …

Patch clam** depends on a tight seal between the cell membrane and the glass of the
pipet. Why does the seal have such high electric resistance? Why does the patch adhere so …