Herein, we report an activatable near‐infrared (NIR) afterglow theranostic prodrug that
circumvents high background noise interference caused by external light excitation. The …

The successful treatment of oncological malignancies which results in long-term disease
control or the complete eradication of cancerous cells necessitates the onset of adaptive …

Simple Summary The combination of disulfiram and copper is a novel anti-cancer drug
under clinical development for the treatment of several tumor types including hepatocellular …

Simple Summary The human body consists of trillions of cells and several million of them die
daily. These natural processes which determine the fate of a cell in the human body can be …

Background Colorectal cancer (CRC) is a highly prevalent cancer type with limited targeted
therapies available and 5-year survival rate, particularly for late-stage patients. There have …

Macroautophagy/autophagy has previously been regarded as simply a way for cells to deal
with nutrient emergency. But explosive work in the last 15 years has given increasingly new …

Organometallic metal (arene) anticancer agents were believed to confer low selectivity for
potential cellular targets. However, the ruthenium (arene) pyridinecarbothioamide (plecstatin …

Purpose Some first-line cytotoxic chemotherapics, eg doxorubicin, paclitaxel and oxaliplatin,
induce activation of the immune system through immunogenic cell death (ICD). Tumor cells …

Background Retrospective clinical trials reported a reduced local relapse rate, as well as
improved overall survival after injection of local anesthetics during cancer surgery. Here, we …

Immunogenic cell death (ICD) has been widely employed to potentiate cancer
immunotherapy due to its capability to activate the anticancer immune response. Although …