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A guide to complement biology, pathology and therapeutic opportunity
Complement has long been considered a key innate immune effector system that mediates
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …
Staphylococcus aureus colonisation and strategies for decolonisation
P Piewngam, M Otto - The Lancet Microbe, 2024 - thelancet.com
Staphylococcus aureus is a leading cause of death by infectious diseases worldwide.
Treatment of S aureus infections is difficult due to widespread antibiotic resistance …
Treatment of S aureus infections is difficult due to widespread antibiotic resistance …
Multimodal nanoimmunotherapy engages neutrophils to eliminate Staphylococcus aureus infections
The increasing prevalence of antimicrobial resistance in Staphylococcus aureus
necessitates alternative therapeutic approaches. Neutrophils play a crucial role in the fight …
necessitates alternative therapeutic approaches. Neutrophils play a crucial role in the fight …
Metal-based nanomaterials with enzyme-like characteristics for bacterial rapid detection and control
B Gao, Q Ye, Y Ding, Y Wu, X Zhao, M Deng… - Coordination Chemistry …, 2024 - Elsevier
Bacterial contamination exists in all links of the food industry chain, and bacterial infections
in clinical treatment have become a major problem in the field of global public health …
in clinical treatment have become a major problem in the field of global public health …
Mechanochemically reprogrammed interface orchestrates neutrophil bactericidal activity and apoptosis for preventing implant‐associated infection
G Chu, M Guan, J **, Y Luo, Z Luo, T Shi… - Advanced …, 2024 - Wiley Online Library
The onset of implant‐associated infection (IAI) triggers a cascade of immune responses,
which are initially dominated by neutrophils. Bacterial aggregate formation and hypoxic …
which are initially dominated by neutrophils. Bacterial aggregate formation and hypoxic …
Staphylococcus aureus Infections and Human Intestinal Microbiota
A Liu, S Garrett, W Hong, J Zhang - Pathogens, 2024 - mdpi.com
Staphylococcus aureus (S. aureus) is a common pathogen that can cause many human
diseases, such as skin infection, food poisoning, endocarditis, and sepsis. These diseases …
diseases, such as skin infection, food poisoning, endocarditis, and sepsis. These diseases …
Novel membrane-targeting isoxanthohumol-amine conjugates for combating methicillin-resistant Staphylococcus aureus (MRSA) infections
R Yang, W Cheng, M Huang, T Xu, M Zhang… - European Journal of …, 2024 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is a widespread pathogen causing
clinical infections and is multi-resistant to many antibiotics, making it urgent need to develop …
clinical infections and is multi-resistant to many antibiotics, making it urgent need to develop …
Understanding the intricacies of microbial biofilm formation and its endurance in chronic infections: a key to advancing biofilm-targeted therapeutic strategies
Bacterial biofilms can adhere to various surfaces in the environment with human beings
being no exception. Enclosed in a self-secreted matrix which contains extracellular …
being no exception. Enclosed in a self-secreted matrix which contains extracellular …
[HTML][HTML] In vitro models for studying implant-associated biofilms-A review from the perspective of bioengineering 3D microenvironments
Biofilm research has grown exponentially over the last decades, arguably due to their
contribution to hospital acquired infections when they form on foreign body surfaces such as …
contribution to hospital acquired infections when they form on foreign body surfaces such as …
Metabolic modulation-mediated antibiotic and Immune activation for treatment of chronic lung infections
The Pseudomonas aeruginosa biofilm in recalcitrant chronic lung infections not only
develops high antimicrobial tolerance but also induces an aberrant host inflammatory …
develops high antimicrobial tolerance but also induces an aberrant host inflammatory …